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Biomedical subjects

S Kaufhold

Publications and source records attributed to S Kaufhold.

3 recordsLinked to original sources

[Numerical studies of the effect of prosthetic implants on the strain energy density distribution in the femur].

In this study the distribution of the strain energy density (SED) in the natural femur as well as changes of it due to the implantation of an artificial hip joint has been investigated. Because of recently published theoretical considerations the volume related SED was used to describe the respective biomechanical loading situation completely. By means of parameter variation different load cases were simulated. The calculated SED-distributions were compared with the respective results of the natural femur. Thus, the known reasons of failures of hip joint prostheses has been proofed numerical. It was shown that the SED is a suitable mechanical parameter to simulate bone remodeling after hip joint replacement.

Biomechanical Phenomena↗

Lipid interference in the determination of the concentration of haemoglobin in plasma using the ACA SX analyzer.

In comparison to a triple wavelength procedure, the dual wavelength method for the determination of plasma haemoglobin concentration using the ACA analyzer showed considerable interference with hypertriglyceridaemic (triacylglycerols > 2.3 mmol/l) plasma. By addition of isolated human lipoprotein fractions to normotriglyceridaemic plasma, chylomicrons were identified as a major source of interference with the ACA plasma haemoglobin method, whereas VLDL was without effect up to a triacylglycerol concentration of 5.7 mmol/l. Airfuge ultracentrifugation proved to be a reliable means for removal of interfering lipid. We conclude that the extent of lipid interference with the ACA plasma haemoglobin method is highly dependent on the type of lipoprotein present. An accurate measurement of plasma haemoglobin concentrations in non-fasting plasma can only be ensured after lipid removal through airfuge ultracentrifugation.

Chylomicrons↗