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S Kelso

Publications and source records attributed to S Kelso.

2 recordsLinked to original sources

Categorization of ambiguous sentences as a function of a changing prosodic parameter: a dynamical approach.

The present study investigates the dynamics of changes in interpretation of ambiguous sentences. The sentences used had alternative interpretations with different surface structures (bracketing). Continua were created by systematic manipulation of prosodic cues (relative foot duration), resulting in stimulus sentences that spanned the range between the two interpretations. Continua were presented to subjects who were requested to indicate as quickly as possible which meaning they perceived. The pattern of responses and response times revealed the presence of hysteresis. That is, when the values of prosodic parameters are congruent with both interpretations, the individual's recent history decides which meaning will be perceived. Thus, we can treat this categorization process as a transition from an initially stable meaning that loses stability with variations in prosody (our control parameter). The same underlying dynamics have been observed in studies of perception of syllables and aspects of visual perception. Apart from demonstrating the same characteristics of pattern formation at various levels of cognition, the study points to the usefulness of the dynamical approach in the investigation of language understanding.

Cognition↗

Intracellular injections of EGTA block induction of hippocampal long-term potentiation.

Hippocampal long-term potentiation (LTP) is a remarkably stable facilitation of synaptic responses resulting from very brief trains of high-frequency stimulation. Because of its persistence and modest induction conditions, LTP represents a promising candidate for a substrate of memory. Some progress has been made in localizing the changes responsible for the effect; for example, it has been shown that LTP is not accompanied by changes in the fibre volleys of the test afferents or by generalized alterations of the dendrites of their target cells. However, it is unknown whether the potentiation is due to pre- or postsynaptic changes and there is evidence in favour of each (for example, see refs 5, 6). We now report that intracellular injections of the calcium chelator EGTA block the development of LTP. These results strongly suggest that LTP is caused by a modification of the postsynaptic neurone and that its induction depends on the level of free calcium.

Animals↗