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Biomedical subjects

S Khadzhiev

Publications and source records attributed to S Khadzhiev.

5 recordsLinked to original sources
PubMed1990

[The morphology of microcolonies as a criterion for recognizing bacteria in the differentiation of Streptococcus pyogenes and Streptococcus group B].

The authors studied the diagnostic importance of the morphology of microcolonies of S. pyogenes and group B streptococci in comparison with the currently used tests for the differentiation of these two species: the bacitracin test, the hydrolysis of sodium hippurate and the CAMP test. The standard tests proved to be positive in 94-97% and microcolonies had typical morphology in 86-95.7%. The statistical indices of the diagnostic effectiveness of differential tests varied within 93.8-98.9%. The diagnostic value of the study of the morphology of colonies was characterized by the following data: the sensitivity and prognostic negative value of the study were 95% for S. pyogenes and 86-89% for group B streptococci, while its specificity and prognostic positive value were 100% due to the absence of false positive results.

Bacteriological Techniques↗
PubMed1987

[Microcolony morphology as a criterion in bacterial diagnosis. The differentiation of Pneumococcus from alpha-hemolytic Streptococcus].

The authors have developed a method permitting the microscopic study of the morphology of bacteria and their relative position in microcolonies. Thus, the use of this method has made it possible to distinguish Streptococcus pneumoniae from other bacteria by the morphology of their microcolonies. In the study of 75 streptococcal strains, all strains yielding positive results in two or three tests, similarly to all strains pathogenic for mice, formed microcolonies with granular (pneumococcal) morphology, while all strains yielding negative results have been found to form microcolonies with catenulate ("nonpneumococcal") morphology. The authors suggest that the morphology of microcolonies is a more reliable criterion for the identification of S. pneumoniae than other tests used separately.

Animals↗
PubMed1976

Survival rate in lung cancer.

The authors followed the survival rate in 927 patients with lung cancer treated in the oncological dispensary of the Plovdiv City during 1965--1972. 41.3% of the patients were in stage 1--11, 19.9%--in stage III, 38.8%--in stage iv. Of all the patients 8.2% were operated upon, in 14.7%--radiotherapy was employed, 9.9% of the patients were treated pharmacologically, 67.5% of cases were not treated at all. As a result of all kinds of treatment 21.4% of the patients survived for one year, and 1.1%--for 5 years. It is concluded that the search for new methods of the treatment and early diagnosis of lung cancer is quite essential.

Bulgaria↗