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Biomedical subjects

S Kiene

Publications and source records attributed to S Kiene.

16 recordsLinked to original sources

[The arterial blood supply of extrahepatic bile ducts of the donor liver].

The discussion of the etiopathogenesis of biliary complications after orthotopic liver transplantation have always encountered the problem of the status of a limited or interrupted blood supply of the ductus hepatocholedochus in the liver graft. For the description of the arterial vascular anatomy of the common bile duct 40 liver specimen were postmortem explanted and injection replica were made using corrosion technique. The arterial structures were systematically analysed and classified on the basis of their origin, distribution, calibre and combination. As a result, two types of arterial blood supply were defined and conclusions drawn for the surgical dissection during hepatectomy of the graft.

Adult

[Malignant tumor of the autonomic nervous system of the stomach (GAN-tumor)--case report of a new entity].

Gastrointestinal autonomic nerve (GAN)-tumors are extremely rare. So far seven cases of intestinal and four of gastric GAN-tumors were reported. GAN-tumors, also termed plexosarcomas, arise from autonomic nervous system plexuses of the gastrointestinal tract such as those of Meissner or Auerbach. We report a case of a metastatic gastric GAN-tumor in a 40-year-old woman. A small, 1 cm in diameter, submucosal plexosarcoma located in the posterior gastric wall and a 1.5 kg, 23 x 15 x 11-cm metastasis located retroperitoneally behind the stomach between liver, spleen and pancreas without discernable invasion of any of these organs were found. En-bloc resection of the retroperitoneal mass, the spleen, the pancreatic tail, and a part of the posterior gastric wall adhering to the mass were performed. In addition, lymph node metastases in splenic hilum were noted, and resected. In CT scan liver metastases were detectable fourteen months after surgery. The diagnosis is based on light microscopical, ultrastructural, and immunhistochemical analyses. The prognosis of GAN-tumors is fatal. In spite of radical excision 8 of 11 reported patients died few month after surgery while local recurrences and/or metastases in regional lymph nodes and in the liver were found. The response to chemotherapy was poor.

Adult

[Animal experiment studies of the distribution and elimination of radioactively marked endotoxin].

We were able reproduce typical morphological and laboratory changes of endotoxinemia in dogs and small experimental animals by administration of E. coli = 111 K58 endotoxin labelled with 99m Tc. Contrary to the literature our distribution studies in rats showed a high concentration of endotoxin in the kidney. An effective endotoxin elimination was possible by extracorporal hemoperfusion in vitro and vivo. Optimal results were achieved using immunoabsorption in combination with plasmapheresis. However, further experimental studies are necessary to clarify the problem fully.

Animals

[Electromyographic and manometric studies of the antrum and duodenal motility in rabbits under the influence of pentagastrin in a mechanical duodenal passage disorder].

The influence of a mechanical disturbance of the duodenum on the motility of the antrum and duodenum was investigated by means of the electromyography and the perfusion manometry. Thereby the effect of the pentagastrin stimulating the motility of the unstriated muscles of the gastro-intestinal tract was used for testing the function reserve of the antrum- and duodenal-muscles. After one and a half month of establishing the passage obstacle there occurs a complex disturbance of the electrical activity; the unstriated muscles does not react on a stimulating excitation.

Animals

[Surgical methods in anal and rectal prolapse].

Anal prolapse in adults is cured by the Milligan-Morgan procedure. Operation for the rectal prolapse has to repair procidentia, incontinence and obstipation. Procidentia and incontinence in low-risk patients are best repaired by abdominal rectopexy with or without plastic materials (Ripstein's procedure is preferred). Obstipation remains a long-term problem. Rectopexy in combination with sigmoid resection (Goldberg) improves obstipation, but there is leakage in 4% of the patients. The perineal approach offers no technical advantage. Perineal rectopexy, prolapse resection and Thiersch ring with modifications are preferred in high-risk cases. Posterior levator plastic improves remaining incontinence.

Fecal Incontinence

[Under the thigh amputation according to Bruckner].

Knee joints of 24 in 28 patients were successfully preserved by below-knee amputation according to Brückner, at the Surgical Department of Karl-Marx University in Leipzig in 1987. The above patients had been in advanced age and in multimorbid conditions. Surgical technique and postoperative care are described and discussed in some detail.

Aged

[Soft tissue plastics in treatment of chronic osteomyelitis (author's transl)].

Soft tissue plastics are indispensable in the surgical treatment oft chronic osteomyelitis (56 cases in 10 years). Myoplastics (27 operations) are simple, successful, but only suitable with stabile bones. The treatment of osteomyelitis in the distal parts of the extremities often requires additional skin flaps (25 operations), rarely free skin grafts.

Adipose Tissue

[Lyophilized split pigskin for biological wound dressings (author's transl)].

Experimental and clinical investigations of an unviable split pigskin preserve, produced by a fairly simple industrial process, outline the following results: The skin preserve protects a wound surface against infection and prevents loss of fluid. The reaction of the wound surface is very restricted even after repeated application, whilst the viable pigskin releases a more intense host reaction.

Animals

[Possibilities and limits of outpatient surgery (author's transl)].

The aims of modern outpatient surgery include: the comprehensive development of ambulatory therapy especially the repertoire of operations, preclinical standardized diagnostic procedures, postoperative outpatient care and rehabilitation. The main reasons for this development are analyzed. In order to make further progress in the direction indicated the number of surgeons working in outpatient departments will have to be increased. Own experiences in outpatient saphenectomy, excisions of Dupuytren's contracture, haemorrhoidectomy, mastectomy, herniorrhaphy, enucleation of cold nodes in the thyreoid gland (171 operations between 1972 and 1974) encourage further efforts in this direction.

Ambulatory Care