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S Kiener

Publications and source records attributed to S Kiener.

4 recordsLinked to original sources

[Reproducibility of fasting serum cholesterol and triglycerides in ambulatory patients with mixed hyperlipidemia].

Intraindividual variability of serum lipid concentrations in normal volunteers and in patients with hyperlipidemia is substantial. The aim of this study was to investigate prospectively the reproducibility of fasting serum triglyceride and total cholesterol concentrations in primary health care patients with combined hyperlipidemia, i.e. under conditions of daily medical practice. Secondary forms of hyperlipidemia were excluded. 19 general medical outpatients with primary combined hyperlipidemia were studied. Serum total cholesterol and triglyceride concentrations were measured after an overnight fast at 08.00 h 4 times at weekly intervals. To study the influence of alcohol intake on serum lipid concentrations, total cholesterol and triglycerides were measured without alcohol influence and 12 hours after consumption of a mean of 100 g alcohol in the evening. In 19 patients (10 males, 9 females, mean age 55 years, body mass index 27.9 +/- 4.4 kg/m2), mean +/- SD of serum triglycerides was 3.97 +/- 1.8 mmol/l and of total cholesterol 7.9 +/- 1.8 mmol/l. The combined intraindividual and interassay coefficient of variation was 18.7 +/- 8.2% for triglycerides and 5.1 +/- 2.5% for total cholesterol. Fasting serum triglycerides (3.5 +/- 1.1 vs. 3.7 +/- 1.4 mmol/l) and total cholesterol (7.6 +/- 1.4 vs. 7.8 +/- 1.0 mmol/l) did not significantly change 12 hours after acute alcohol consumption. Patients with primary combined hyperlipidemia in a primary health care setting show small intraindividual variations of overnight fasted serum triglyceride and total cholesterol concentrations. Moderate alcohol consumption 12 hours before blood sampling does not significantly affect triglyceride and cholesterol values.

Adult↗

[Processing steps in perception of speech sounds].

The aim of this study is to investigate whether speech sounds--as is stated by the widely accepted theory of categorical perception of speech--can be perceived only as instances of phonetic categories, or whether physical differences between speech sounds lead to perceptual differences regardless of their phonetic categorization. Subjects listened to pairs of synthetically generated speech sounds that correspond to realizations of the syllables "ba" and "pa" in natural German, and they were instructed to decide as fast as possible whether they perceived them as belonging to the same or to different phonetic categories. For 'same'-responses reaction times become longer when the physical distance between the speech sounds is increased; for 'different'-responses reaction times become shorter with growing physical distance between the stimuli. The results show that subjects can judge speech sounds on the basis of perceptual continua, which is inconsistent with the theory of categorical perception. A mathematical model is presented that attempts to explain the results by postulating two interacting stages of processing, a psychoacoustical and a phonetic one. The model is not entirely confirmed by the data, but it seems to deserve further consideration.

Adult↗