Biomedical subjects

S Kishel

Publications and source records attributed to S Kishel.

3 recordsLinked to original sources

PubMed1998

Partial lung shield for TBI.

In this study, AP/PA setup was used with a 4 MV linear accelerator. The prescribed dose is 1000 cGy, with a dose per fraction of 200 cGy. One of the simplest lung dose determinations is the nomograph relating dose correction factor and patient thickness. To save time in taking port film in every treatment, lung block is used in alternating fashion: anterior blocks are used in the second and fourth fraction and posterior block is used in the third and fifth fraction. If we set the average correction factor for the lower density lung to 1.18, the six open fields will deliver an average of 708 cGy to the lung. To limit the lung dose to 10 Gy, each blocked field should deliver 73 cGy. Measurements showed that a thickness of slightly less than 1 cm of cerrobend provides approximately 65% transmission, which approximates the desired 73% broad beam transmission. The proper transmission of the partial lung shield is verified by measurements made for the patients with diodes placed at the entrance and the exit side of the lung. While we describe a particular setup, the procedure can be modified to accommodate different dose fraction. There are many ways to deliver the TBI dose, and the method of constructing the partial lung shield described here is one of the many methods that may be used to limit the dose to the lung.

Humans↗

PubMed1995

A simple device for prostate and rectal localization in radiation therapy.

A simple device for prostate and rectum localization in radiation therapy may be constructed as follows: first, dental wax is used to make up a shape of the rectal probe. Second, dental stone is used to make a two-piece mold by molding the dental wax probe. Third, using the mold, the rectal probe is made from a mixture of silicone and barium. The final step involves the attachment of the "plug," which is made of aluminum. From the simulation films for the prostate setup, the location of the anterior wall of the rectum, anal sphincter, and anal verge can easily be identified, such that the appropriate regions are shielded accordingly. A CT scan with the probe in the rectum did not give too much artifacts from the barium/silicone mixture. The rectal probe with the plug is useful for localizing the prostate more accurately, compared with using the other rectal localization techniques such as barium injection or some rectal markers.

Aluminum↗

PubMed1984

Effect of sodium meclofenamate on radiation-induced esophagitis and cystitis.

Stumptailed monkeys (Macaca arctoides) received 2000 rad irradiation to the upper half of the esophagus and to the bladder by a 6-MEV linear accelerator. Endoscopy and biopsy was obtained from these organs weekly for 3 weeks. At the end of this period, the animals were autopsied and histopathologic examination undertaken. Sodium meclofenamate in doses of 5-20 mg/kg/day p.os was found effective in reducing or preventing radiation induced esophagitis and cystitis.

Animals↗