Ideas about the surface runoff features on Mars.
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Extraterrestrial Environment↗
Biomedical subjects
S Klonowski
Publications and source records attributed to S Klonowski.
[The use of microsurgery and balneotherapy in the treatment of hyperplastic laryngitis].
The study aimed at the assessment of the clinical value of using the combined method of laryngeal microsurgery and balneotherapy in the operative treatment and prevention of recurrences of limited hyperplastic changes of the laryngeal mucosa. The study material comprised two groups of patients diagnosed and treated in the years 1991-1997 in the Lublin E.N.T. Department and Laryngological Research-Consulting Center in Iwonicz Zdrój. The I clinical group consisted of 194 patients in whom, on definite indications, micro-surgeries with Kleinsasser's method were performed and the II control group consisting of 165 subjects suffering from chronic simple inflammation of pharyngo-laryngeal mucosa without morphologic hypertrophy. Inhalant treatment was performed by means of an individual method--using inhalant devices by Thomex L-2 producing high density mist of 1-4 mu degree comminution. Isotonic Iwonicz saline-Elin 7 was used. Uniform criteria of assessment were assumed and used of direct and distant therapeutic effect (in control studies) for the whole group of patients in the study period. Obtained results were analysed statistically.
Adult↗
Injuries of the middle ear with a welding spark.
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Adult↗
Expression of bcl-2 protein in lymphocytes of patients with laryngeal carcinoma.
The aim of this study was to evaluate the expression of bcl-2 protein in lymphocytes of the peripheral blood of patients with laryngeal carcinoma. The protein product of the proto-oncogene bcl-2 is a physiological inhibitor of apoptosis or programmed cell death. Since we believe that apoptosis is involved in the regulation of an immune response to a cancer process, we tried to show how this mechanism works in laryngeal carcinoma in comparison with normal peripheral blood lymphocytes of healthy controls. To explain the significance of this molecule's expression, we used flow cytometry to examine the expression of bcl-2 in T lymphocytes from the peripheral blood of 23 patients with laryngeal carcinoma and 20 healthy controls. Our study revealed that the expression of bcl-2 protein in T lymphocytes from the cancer patients was significantly higher than in the controls (P < 0.05). This difference in the expression of bcl-2 protein was found in both CD4 and CD8 subpopulations and was significantly higher than in the control group. In patients with laryngeal carcinoma expression of bcl-2 protein in T lymphocytes was higher in CD4 than in CD8 cells (P < 0.05). These results suggest that bcl-2 protein may interact in the regulation of apoptosis of lymphocytes, taking part in anti-cancer defence.
Adult↗
Tumor angiogenesis in patients with laryngeal cancer.
Tumor angiogenesis was evaluated in 60 patients with primary laryngeal cancer by quantitating the microvessel density with antibodies against factor VIII. The microvessel density was then correlated with T stage, N stage, histologic grade and patient survival. A direct correlation was found between increased tumor angiogenesis and T stage, histologic grade and a shorter survival rate.
Adult↗
Microsurgery and balneotherapy in the treatment of hyperplastic laryngitis.
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Adult↗
The effect of working environment on mucous membrane of the upper respiratory tract and organ of hearing in miners of the Lublin Coal mines.
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Air Pollutants, Occupational↗
[Epidemiologic and clinical tests of patients suffering from laryngeal cancer in the Lublin macro-region in the years 1991-1995].
The study of registered morbidity of patients suffering from laryngeal cancer in the Lublin macro-region in the years 1991-95 was carried out. Morbidity rates in the population in consecutive years of investigated 5-year age groups were examined. In clinical investigations the conditions of clinical advancement of the disease in particular organs was determined and environmental factors and occupation were also revealed.
Adult↗
[The reasons for failures of laryngeal cancer surgeries].
In 4 ENT Clinics of Medical Academies in Poznań, Warszawa, Kraków, Lublin 2620 laryngeal cancer patients were operated upon during the years 1980-1987. The treatment failure occurred in 760 cases (29%). The following possible to discover factors were probably responsible for unsuccessful results: senility, other concomitant diseases (especially cardiac), prolonged diagnostic procedure, no up to date diagnostic methods, giving up the radiotherapy (38% of cases), upper laryngeal localization of tumors (87%), advanced extents T3 and T4 (83%), advanced clinical stages of cancer (III degrees and IV degrees 85%), lack of surgical radicality especially in neck dissection, unsuccessful neck dissection behind the accessory nerve, omittance of taking the specimens to the pathomorphologic examinations from the marginal part of the operational field in 25% of patients. The early recurrences in these places in apart of patients spoke for the presence of the neoplasmatic cells in this region.
Adult↗
[Application of intralaryngeal submucous chordectomy in the treatment of bilateral vocal cord paresis].
The article presents long-term results of operative treatment of 128 patients with bilateral vocal cord paresis. The best functional results, for all the 128 operated cases, were obtained with the use of the method of intralaryngeal submocous chordectomy, with partial arytenoidectomy performed according to the technique of laryngeal microsurgery. However, considerably poorer results were obtained in those cases where the classic Surjan method was used, or our own modifications of this method.
Adolescent↗
[Epidemiologic and clinical investigations of patients suffering from laryngeal neoplasms in the Lublin region in the years 1991-1994].
Investigations of larynx cancer rate of Lublin population were carried out in the years 1991-1994. Factors of the community rates in each year and in five-years age group were determined. 681 suffering people were examined clinically. The clinical stage and degree of organ involvement were appointed.
Adult↗
[Failure of surgical treatment in patients with laryngeal cancer].
In 4 ENT Clinics of Medical Akademies in Poznań, Warszawa, Kraków, Lublin 2620 laryngeal cancer patients were operated upon during the years 1980-1987. The treatment failure occurred in 760 cases (29%). The following possible to discover factors were probably responsible for unsuccessful results: prolonged diagnostic procedure, upper laryngeal localization of tumors, advanced extents T3 and T4 (83%), advanced clinical stages of cancer (III degree and IV degree 85%), lack of surgical radicality especially in neck dissection. The early recurrencies in these places in apart of patients spoke for the presence of the neoplasmatic cells in this region.
Combined Modality Therapy↗
[Distant results of surgical treatment in patients with carcinoma of the larynx].
Three and five years survival rates in a group of 3440 patients surgically treated for carcinoma of the larynx in four ENT Departments in the years 1977-86 were presented. 5 years survival rate was obtained in 70% of patients treated only surgically, and in 46% patients treated with surgery combined with radiotherapy.
Carcinoma↗
[Microlaryngoscopy and microsurgery in diagnosis and treatment of laryngopathies].
In the Otolaryngology Clinic of the Medical Academy in Lublin in the 21 year period (1971-1991) there were performed 2488 microsurgical operations of the larynx. The authors analyse their own clinical material paying particular attention to relative precancer states, early diagnosis of laryngeal cancer and an increase of the number of preinvasive cancer (cancer in situ) diagnoses. The authors postulate that indications for clinical diagnostic and therapeutic procedures should be considerably extended in diseases of the larynx. There should be used an operating microscope which will considerably shorten hospitalization period of patients and significantly contribute to an increase of the percentage of early diagnoses of cancer of the larynx.
Female↗
[Serum ceruloplasmin activity in patients with cancer of the larynx].
The ceruloplasmin activity of serum was measured in 50 patients with larynx cancer and 50 healthy subjects. The determination of serum ceruloplasmin based on the diamine oxidase activity with o-dianisidine as a substrate. In patients with laryngeal cancer the ceruloplasmin activity was significantly higher than that in healthy controls. The increase in the ceruloplasmin activity was correlated with clinical stage of larynx cancer.
Adult↗
[Evaluation of the healing value of Iwonicz mineral water in balneo-climatic therapy of chronic hyperplastic laryngitis with wide pachydermic changes of laryngeal mucous membrane after microsurgery by the Kleinsasser method].
The paper comprises clinical estimation of using Iwonicz mineral water Elin 7 in balneotherapy of chronic hyperplastic laryngitis after its microsurgical therapy by Kleinsasser method. Investigation in the group of 246 people showed that combined treatment, i.e. microsurgery and balneotherapy, is an effective method of healing some hyperplastic inflammatory diseases of mucous membrane of the larynx.
Adult↗
[Results of the treatment of parotid gland tumors].
During the years 1977-1986 84 patients with the parotid tumor were treated in ENT Clinic in Lublin. 16.6% of tumors were malignant. The surgical procedure was performed in 74 cases (84.5%). There were the removal of tumor with or without the parotid gland resections. In all cases of resection the facial nerve was saved. In malignant tumor cases the radiotherapy followed the surgery. 13 patients with poor health conditions were treated without surgery. The early and late results were described.
Adenolymphoma↗
[Use of computerized tomography in topographic diagnosis of salivary gland tumors].
In the radiologic assessment of extension tumors of parotid glands CT method was used and for comparative purposes sialography was performed. In comparative analysis there was assessed CT method and its usefulness in the preoperative assessment of tumor extension.
Adenoma, Pleomorphic↗