The anatomic radiological patterns of the venous drainage of the pancreas were studied in 20 dogs, utilizing injection of Schlesinger mass by means of catheter placed on the cranial mesenteric, portal and splenic veins. The drainage of the cranial 2/3 of the right lobe of the pancreas is made by the cranial pancreaticoduodenal vein, while the caudal third is made by the caudal pancreaticoduodenal vein. There are communications between these two veins. The drainage of the angular pancreatic portion in made by venous branches which drain in the gastroduodenal vein. Conversely the drainage of the cranial portion of the left lobe is made by venous branches which drain in the gastroduodenal vein or in the portal vein. The caudal portion is drained by a variable number of veins which are tributary of the splenic vein and a communication between the venous branches from the caudal and cranial portion of this lobe are present in 8 of the 20 dogs studied. The authors emphasize the importance of the careful knowledge of the pancreatic venous anatomy in order to present misinterpretation of the physiological and physiopathological events observed in research which utilizes the dog as the experimental animal.

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PubMedDate not supplied

[Sodium diclofenac effect, after interruption of the stercoraceous peritonitis, on the rat colon. Study of mechanical resistance and collagen concentration].

UNLABELLED: The objective of the present study was to investigate changes in colon wall in rats with fecal peritonitis (Per) associated with sodium diclofenac (SD) by studying breaking strength and tissue collagen concentration. The rats were divided into the following experimental groups: GROUP 1-SD: 60 animals injected intramuscularly with sodium diclofenac at the dose of 2 mg/kg body weight; GROUP 2-Per: 60 animals injected intraperitoneally with a suspension of human feces. Peritonitis was interrupted after six hours of evolution; GROUP 3-Per+SD: 60 animals injected intraperitoneally with a suspension of human feces and receiving SD according to the schedule used for Groups 1 and 2; CONTROL GROUP: 12 animals injected intramuscularly with physiological saline. The animals of Group 1, 2 and 3 were successively sacrificed 2, 4, 7, 14 and 21 days after interruption of peritonitis an/or the beginning of treatment. Under conditions of the experimental model and of the methods used, we conclude that sodium diclofenac, peritonitis and the peritonitis-sodium diclofenac association decrease the breaking strength and the concentration of tissue collagen in the colon segment.

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