PubMed Health⌕ Search

Biomedical subjects

S Korsager

Publications and source records attributed to S Korsager.

6 recordsLinked to original sources
PubMed1979

Iodine-induced hypothyroidism and its effect on the severity of asthma.

Among 1107 patients with asthma or chronic asthmatic bronchitis and 96 with hypothyroidism we found 12 patients with both diseases. Seven of these patients had hypothyroidism induced by iodine-containing expectorants. Five of 209 patients with hyperthyroidism had coexistent asthmatic lung disease, but none of these five had been taking iodine. The severity of asthma is considered in relation to changes in thyroid function following withdrawal of iodine. Three patients had an exacerbation of their asthma, while another three had no change in their asthma when the iodine treatment was discontinued and the euthyroid state subsequently restored. All six patients had a marked improvement of their general wellbeing when the euthyroid state was re-established. It is concluded that treatment with iodine-containing expectorants causing hypothyroidism is unwise and should be withdrawn even when the patients praise the beneficial effect of iodine on the asthma per se.

Aged↗
PubMed1979

Thyroid replacement therapy in Down's syndrome with hypothyroidism.

Three elderly subjects with Down's syndrome and biochemical evidence of hypothyroidism were investigated before and after four months of thyroid replacement treatment. The patients' appearance was demonstrated by photographs and the biochemical thyroid values and the intellectual performance were assessed. The appearance before treatment varied from a florid myxoedematous appearance to a state without features indicating myxoedema. Thyroid replacement therapy was given in usual dose and the biochemical response was similar to that seen in normal subjects. The intellectual performance improved little or not at all. The characteristic discomfort usually associated with hypothyroidism was very pronounced in one case and disappeared totally during treatment. It is concluded that the diagnosis of hypothyroidism in elderly subjects with Down's syndrome can be very difficult when based on appearance and history alone and biochemical thyroid tests are often necessary. The patients should be treated with replacement therapy just as other patients suffering from hypothyroidism.

Down Syndrome↗
PubMed1979

Sarcoidosis of the stomach. A case report.

A case of sarcoidosis of the stomach in a 76-year-old woman is described. Fiberoptic gastroscopy and roengenograms presented the appearance of an infiltrating carcinoma. It was possible to follow the spontaneous behaviour or roentgenograms during a period of 4 years. A preceding, spontaneously remitted lesion of the lungs is described, and the lack of parallelism between the two lesions is discussed. The case is seen in the light of other cases described in the literature, and the difficulties concerning the differential diagnosis are discussed.

Aged↗
PubMed1978

Thyroid function tests in adults with Down's syndrome.

Thyroid status was studied in 24 patients above the age of 40 years with Down's syndrome. Three patients had thyroid function tests indicating hypothyroidism. Eight patients had thyroid autoantibodies in serum and 8 patients had a higher than normal level of thyroid stimulating hormone in serum. None of the patients had figures indicating thyrotoxicosis. None of the patients showed any of the clinical signs usually seen in patients with hypothyroidism. It is concluded that biochemical tests indicating hypothyroidism are much more often seen in patients with Down's syndrome than in normal subjects and that thyroid status should be assessed in old patients with this disease.

Adult↗