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S Koseki

Publications and source records attributed to S Koseki.

3 recordsLinked to original sources

Dynamic exercise echocardiography.

To evaluate left ventricular (LV) reserve, we developed a method of dynamic exercise echocardiography (DEE). Forty-six healthy persons and 47 cardiac patients performed bicycle ergometer exercise in the supine position. A special table was used on which the subjects could be firmly attached at shoulder level to prevent bodily movements which might disturb the recordings. In 83% of the subjects in whom a clear echocardiogram was obtained at rest, a clear echocardiogram was also obtained during dynamic exercise. During exercise, cardiac output estimated from the echocardiogram and that from the dye-dilution method showed an excellent correlation. The changes of the mean velocity of LV circumferential shortening during exercise permitted discrimination between older and younger healthy men, and also between healthy subjects and those with either mild or severe LV dysfunction. We conclude that DEE is useful for evaluating LV reserve.

Adult

Secondary diabetic retinopathy in chronic pancreatitis.

We found abnormal glucose tolerance curves in 45 of 47 patients with chronic pancreatitis and observed secondary diabetic retinopathy in eight of 45 cases showing slight changes in the fundus. Abnormal glucose tolerance curves were somewhat related to the exocrine dysfunction of the pancreas. Slightly abnormal glucose tolerance curves were observed frequently in patients with chronic pancreatitis, and both insulin and glucagon responses were decreased. We could not explain the cause of the low frequency of secondary diabetic retinopathy in pancreatic diabetes from the results of insulin and glucagon response tests.

Adult