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Biomedical subjects

S Kruś

Publications and source records attributed to S Kruś.

At least 37 records · Page 2Linked to original sources
PubMed1984

Metaplasia of the lung respiratory epithelium and antibody dynamics in mice repeatedly infected with various subtypes of influenza virus A.

Mice were repeatedly infected with consecutive doses of mouse-adapted strains of influenza virus A HON1, H1N1, H2N2, and H3N2. Homo- and heterologous antibody levels as well as the incidence of metaplasia were followed. Statistically significant correlation was found between the metaplasia incidence and higher level of antibodies homologous to virus used for a given challenge dose.

Animals↗
PubMed1984

The dynamics of serum antibodies and metaplasia of the lung respiratory epithelium in influenza-virus-preimmunized mice subjected to immunosuppression.

Mice preimmunized with influenza virus A Scotland 840/74 H3N2 were given cyclophosphamide or hydrocortisone, then challenged with the same active virus. Serum antibody levels and metaplasia of the respiratory epithelium were followed for the next two weeks. Administration of the immunosuppressors was found to decrease antibody levels, and to delay the appearance of metaplasia by 7 days as compared with controls.

Animals↗
PubMed1980

Influence of renal denervation on urine concentration in awake and anaesthetized dogs.

The role of renal nerves in urine concentration was studied in clearance experiments with unilaterally renal-denervated dogs prepared by surgical bladder division. Urine concentration was assessed under conditions of: (1) stimulation of ADH release by dehydration or barbiturate anaesthesia; (2) mannitol diuresis, and (3) isotonic saline diuresis. Differences in TcH2O/GFR between the intact and denervated kidney were not significant in any of the experimental groups. However, in dehydrated conscious dogs Uosm of the intact kidney (939 +/- 58 mmol/kg H2O) was significantly higher (P less than 0.05) than that of the denervated organ (806 +/- 51 mmol/kg H2O). In the intact kidney the medullary content of total solutes and sodium per kg wet tissue was 684 +/- 26 mmol and 208 +/- 12 mmol, respectively. This was significantly higher (P less than 0.005) than corresponding values of 581 +/- 23 mmol and 171 +/- 14 mmol per kg wet tissue measured in the denervated organ. We suggest that a slight impairment of urine concentration (lower Uosm) in the denervated kidney of conscious dogs may depend on decreased medullary hypertonicity.

Anesthesia↗
PubMed1978

Glomerular foam cells in kidney allograft.

Foam cells are occasionally encountered in renal glomeruli in cases of nephrotic syndrome, however, they were not described so far in renal allografts. The authors found the glomerular foam cells in a cadaveric kidney transplant which survived 7 months after transplantation in a 35-year-old man. Electron microscopy revealed the mesangial cells to be loaded with lipids in this case. The formation of the glomerular foam cells is generally referred to hyperlipidemia, but its cause remains obscure in the presented case.

Adult↗
PubMed1975

Comparison of the role of testosterone and methyltestosterone in developing chloroform-induced renal tubular necrosis in mice.

The presence of testosterone is a prerequisite for the development of chloroform-induced renal tubular necrosis in mice. The purpose of this study was to check whether methyltestosterone exerts the same influence. Castrated males and females were treated with one of these compounds: those treated with testosterone developed renal tubular necrosis after chloroform injection, those which received methyltestosterone were free of this lesion.

Acute Kidney Injury↗