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Biomedical subjects

S Kunavisarut

Publications and source records attributed to S Kunavisarut.

4 recordsLinked to original sources

Dacryocystorhinostomy at Ramathibodi Hospital.

Two hundred and seventy patients with idiopathic obstruction of the lacrimal passage between the sac and the nasolacrimal duct, who underwent external dacryocystorhinostomy at the Department of Ophthalmology, Ramathibodi Hospital were studied retrospectively. All the patients had the operations between 1983 and 1987; 240 were female (88.9%) and 30 were male (11.1%), with, a ratio of 8 female to 1 male. The ages ranged from 3 to 83 years, with the peak in the 46-55 age group (25.19%). The overall surgical success rate was 86.5 per cent, the definition for success being a relief of the obstruction as evident symptomatically and by the ability to irrigate the saline from the puncta to the nasal cavity at follow-ups of more than 21 days postoperatively. The patients were further subdivided into the "silastic" group and the "non-silastic" group: and the success rate were 75.5 and 95.7 per cent respectively. Significant complications of the dacryocystorhinostomy were recorded in 11 cases; 2 wound infections, 2 lacrimo-cutaneous fistulae, 5 severe operative hemorrhage and 2 ethmoidal sinus involvement.

Adolescent

Challenge of the two neural tumors: neuroblastoma and retinoblastoma.

Fifty cases of neuroblastoma and 29 retinoblastoma patients who had additional chemotherapy were analyzed retrospectively. Male:Female ratio were 1:1 and 0.8:1, the ages ranged from birth to 14 years (4 +/- 3.42 year) for neuroblastoma, and one month to 5.5 years (2.4 +/- 1.4 year) for retinoblastoma. More than 70%-90% of them came in advanced stages. The treatment consisted of surgical resection, enucleation or exenteration if feasible. Radiation therapy and chemotherapy were given as specific and palliative measures. All of the neuroblastoma who were younger than 8 months old survived long-term. Various chemotherapeutic agents did not seem to effect the outcome of the advanced cases of these two diseases. The retinoblasts did not seem to be sensitive to MTX and Ara-C. Thio-tepa intrathecally seems to be worth trying. Since these two tumors are not sensitive to treatment and are still a great challenge to the developed countries, awareness of the diseases, early diagnosis and early treatment are appropriate approaches for the developing countries.

Adolescent