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Biomedical subjects

S L Cunha

Publications and source records attributed to S L Cunha.

10 recordsLinked to original sources

Funduscopic alterations in SS and SC hemoglobinopathies. Study of a Brazilian population.

Fundus changes in sickle cell disease are well studied and documented according to their clinical and angiographic aspects. Sickle cell retinopathy was studied in a Brazilian population of 63 patients (41 with SS hemoglobinopathy, and 22 with SC hemoglobinopathy). All ophthalmoscopic changes observed in our patients were more frequent in the SC group with the exception of atrophic retinal tears, found only in the SS group. Proliferative retinopathy including its complications was seen in 54.54% of the eyes of the SC group, and in only 14.64% of the eyes of the SS group. Decreased vision is consequently greater in the SC group. Despite the great frequency of funduscopic changes in both groups, only 1 patient suffered irreversible visual loss due to retinal detachment operated on without success.

Adolescent

Osseous choristoma of the choroid. A familial disease.

Two patients in the same family (daughter and mother) had osseous choristoma of the choroid in four otherwise normal eyes. The clinical diagnosis of the choroidal lesion was confirmed by B-scan ultrasonography. Both patients were followed up for five years and neither showed any essential change of the fundus. The high prevalence of this choroidal tumor in girls and women (20 of 22 reported cases) and the present report on two patients in the same family suggest that a hereditary factor should be considered in the etiology of this unusual choroidal lesion.

Adult