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S L Hinrichsen

Publications and source records attributed to S L Hinrichsen.

11 recordsLinked to original sources
PubMed1996

Regional training in AIDS prevention for health and behavioural science leaders in north-eastern Brazil.

This article reports results of a World AIDS Foundation-funded training programme in North-Eastern Brazil. Training objectives were: (1) to increase the effectiveness of existing medical and behavioural HIV-related services; (2) to prepare professionals to implement and evaluate social skills-based AIDS prevention programmes incorporating metacontingency systems; (3) to prepare professionals to disseminate training content in North-Eastern Brazil; and (4) to promote local involvement in regional AIDS programme planning. Fifty-eight health and behavioural sciences leaders from 5 North-Eastern Brazilian states represented a variety of institutions actually or potentially involved in AIDS prevention. Training activities focused on programme planning and evaluation and social skills training. Written pre- and post-test data indicate that all participants had a basic understanding of AIDS transmission at baseline. Significant knowledge increases (p < 0.01) resulted in all domains trained except for programme evaluation. For the two social skills evaluated (Condom Use Negotiation and Social Skills Trainer), significant improvements (p < 0.01) resulted in verbal and non-verbal content, assertiveness and anxiety, with the exception of near-significant levels (p < 0.10) achieved for assertiveness and anxiety on the 'Trainer' skill. Participants cofacilitated follow-up trainings in their respective states. These trainings demonstrated a successful model for technology transfer. More focused training is needed in programme design and evaluation methods.

Acquired Immunodeficiency Syndrome↗
PubMed1996

[Cerebrospinal fluid in 50 AIDS patients].

Fifty AIDS patients were studied. All patients had anti-HIV antibodies (ELISA) present and met OPAS/Caracas punctuation criteria for AIDS cases in adults. Cerebrospinal fluid (CSF) analysis included pressure, cytology (number of cytomorphological aspects), total protein and electrophoresis, glucose and chloride concentration. Bacteriological and mycological investigations were performed as well as agglutination tests for Cryptococcus. Complement fixation, indirect immunoflorescence, passive hemagglutination and/or ELISA tests were performed for syphilis, toxoplasmosis, viral and fungal infections. All CSF analysis were made in the same laboratory following the same methodology. CSF was altered in 45 cases (90.0%) of the 50 patients studied. The most important alterations observed were: gammaglobulin (55.5%) and total protein (51.1%) increase, hypercytosis (48.9%) and decrease of chloride concentration (40.0%). HIV antibodies were detected in 42 patients (93.3%). Toxomoplamosis, isolated or associated to other agents, was the most frequent opportunistic infection (57.7%). Cerebrospinal fluid should always be examined in AIDS patients with or without neurological symptoms.

Acquired Immunodeficiency Syndrome↗
PubMed1996

[Cerebral malaria and AIDS: case report].

Although it has not been definitely proven that the severity of malaria is associated to human immunodeficiency virus (HIV) we know that infection through Plasmodium falciparum can favor a rapid evolution of the HIV infection. Besides, association of malaria with HIV/AIDS from a clinical point of view can be clinically severe in the face of the occurrence of other microorganisms or neoplasias, which worsens the evolution and prognosis of the affected patients. The concurrence of HIV with Plasmodium in malaria endemic zones is a possibility which should always be taken into consideration, since transmission is related to risk factors caused by people's behavior which are not always promptly revealed and/or identified. The authors report one case of brain malaria infection by Plasmodium vivax and Plasmodium falciparum in a patient with AIDS. They describe the clinical evolution and therapy.

Acquired Immunodeficiency Syndrome↗
PubMed1993

[Involvement of the nervous system in leptospirosis. I. Evaluation of neurologic aspects].

From January 1st up to September 30th 1990, 77 patients with leptospirosis confirmed by laboratory studies were admitted at the Infectious and Parasitic Diseases Service of the Hospital das Clínicas of the Universidade Federal de Pernambuco. Clinical manifestations had sudden onset with presence of fever, headache, chills and muscle pains. Plurisystemic involvement was observed both in the icteric and in the non-icteric patients. The neurological exam was abnormal in 70 of the patients (90.91%). Neurological findings were essentially variable. Though in a transitory form, they allowed the observation of the following clinical forms: meningoencephalitis and polyneuritis in association, meningoencephalitis, polyneuritis, and subarachnoid hemorrhage.

Central Nervous System Diseases↗
PubMed1993

[Involvement of the nervous system in leptospirosis. II. Cerebrospinal fluid evaluation].

From January 1st up to September 30th 1990, 77 patients with leptospirosis diagnosis confirmed by laboratory studies were admitted at the Infectious and Parasitic Disease Service of the Hospital das Clínicas of the Universidade Federal de Pernambuco. The neurological exam was abnormal in 70 of the patients (90.91%). The cerebrospinal fluid (CSF) examination was carried out on 67 (87%) of the patients; it was abnormal in 64 (95.52%) yielding hypercytosis in the majority of cases. There was no difference in the CSF behavior in report to the several neurological forms nor in relation to the icteric or non-icteric forms of the disease. Significant were the results for the microscopic agglutination tests for leptospirosis in the CSF.

Central Nervous System Diseases↗
PubMed1993

[Involvement of the nervous system in leptospirosis. III. Immunologic reactions in the blood and cerebrospinal fluid].

From January 1st up to September 30th 1990, 77 patients with leptospirosis were admitted at the Infectious and Parasitic Diseases Service of the Hospital das Clínicas of the Universidade Federal de Pernambuco. The majority (64) were male patients, and average age was 28 years old. Serovars icterohaemorrhagic and canicola were the most frequent. CSF examination was performed in 67 (87.0%) patients and it was abnormal in 64 (95.52%). Micro-agglutination test for leptospirosis with live antigens was performed in CSF, as well as immunological tests for syphilis, cysticercosis and schistosomiasis for differential diagnosis. Concerning the serovar identification, results of microagglutination test for leptospirosis in CSF were significant considering the similitude of responses when compared to those found for blood samples.

Adolescent↗
PubMedDate not supplied

[Sodoku--a case report].

Rat-bite fever results from an infection with the organism Spirillum minus. The authors report a symptomatic patient with fever, malaise, and ulcer in forehead after a rodent exposure. The organism was identified in darkfield examination of the ulcer exudate. Penicillin was the drug used with clinical improvement of symptoms.

Adult↗
PubMedDate not supplied

[Management of AIDS during traditional hospitalization and at outpatient clinics in Recife (Brazil)].

The management of 50 AIDS patients by traditional hospital admission (25 cases) and outpatient clinics (25 cases) was studied between August and November 1995 in the Department of Infectious and Parasitic Diseases of the Federal University Hospital. The most costly items of expenditure were hospital services and consumable materials. Comparison of costs was complicated by differences in clinical status of the patients in the two groups. The choice of treatment was much more dependent on clinical status than on sociodemographic factors. Traditional hospital admission tended to be associated with the poorest patients. The rationalization of care based on cost-benefit analysis requires much future work.

Acquired Immunodeficiency Syndrome↗