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Biomedical subjects

S L Librach

Publications and source records attributed to S L Librach.

10 recordsLinked to original sources

Discussion of death and dying in surgical textbooks.

BACKGROUND: Quality end-of-life care is an increasing concern for the public and the medical profession. Surgical textbooks could serve as an important educational and reference resource to improve this care. METHODS: Four general surgical textbooks were scored for helpful information on death and dying for eight surgical diseases. For each disease, nine content domains related to care of the dying patient were evaluated. Three texts included a chapter on cancer that was evaluated separately. RESULTS: Disease epidemiology, prognosis/prevention, progression, and medical interventions were generally well discussed in all textbooks. However, little helpful information was provided with regards to breaking bad news/advanced care planning, mode of death, treatment decision-making, effect on family/surgeon, and symptom management. Cancer chapters also addressed only a few of these concerns. CONCLUSION: Death and the dying patient are sufficiently frequent in surgical practice that it would be appropriate to increase the amount of information provided.

Bibliometrics↗

The principles of palliative radiotherapy: a palliative care physician's perspective.

The relationship between oncology and palliative care is an evolving one. As one debates the processes of palliative radiotherapy, it is important to realize that "palliation" and "palliative care" are not synonymous. We need to explore the definition of palliative care, the myths surrounding palliative care and dying, the need for optimizing pain management and, finally, access to palliative radiotherapy and palliative care.

Humans↗

Special issues in pain control during terminal illness.

Pain control is still a prime concern in managing patients with terminal illnesses, such as AIDS and cancer. I review some special issues that confront family physicians providing such care. Issues include common blocks to good pain management, understanding different types of pain, and the appropriate use of adjunct analgesic drugs and therapies.

Acquired Immunodeficiency Syndrome↗

Managing chronic pain in family practice.

Pain is common in family practice. In dealing with chronic pain, both the family physician and the patient often have problems in defining and in understanding the origin of chronic pain and in providing effective pain relief. This article explores a practical, holistic approach to understanding and managing chronic pain.

Adult↗

Mouse myeloma. A model for studies of cell kinetics.

The mouse plasma cell tumor Adj PC-5 grows slowly due to a large loss of cells from the growth fraction into nonprolifeative, end-stage cells. All tumor cells with the capacity to form a colony appear to be in cell cycle. Marked tumor specificity of several alkylating agents could not be explaned by differences in the porliferative state of myeloma and normal marrow cells. The sensitivity of different mouse myelomas to an alkylating agent varies considerably. The factors determining whether a mouse myeloma is sensitive to an alkylating agent are probably related to structure of the agent and intrinsic properties of the cell, rather than to the agent's mechanism of action.

Alkylating Agents↗