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Biomedical subjects

S L Lindsay

Publications and source records attributed to S L Lindsay.

5 recordsLinked to original sources
PubMed1990

Effect of low-dose butorphanol on halothane minimum alveolar concentration in ponies.

Minimum alveolar concentration (MAC) for halothane was measured before and after administration of intravenous butorphanol (0.022 and 0.044 mg/kg in bodyweight in nine yearling Shetland ponies. Arterial blood pressure, heart rate, respiratory rate, expired CO2 and rectal temperature was also measured. Even though mean MAC values decreased 10 and 9 per cent after the low and high doses respectively, they were not statistically different from those measured prior to butorphanol. Halothane MAC values increased after butorphanol in two ponies, both animals increasing locomotor activity and demonstrating apparent central nervous system stimulation. No significant differences were seen in any variable measured after butorphanol administration.

Anesthesia↗
PubMed1988

Intra-ocular pressure changes during rapid sequence induction of anaesthesia. A comparison between thiopentone and suxamethonium and thiopentone and atracurium.

The changes in intra-ocular pressure associated with two different anaesthetic induction and tracheal intubation techniques were compared (n = 30). After pre-oxygenation, Group A received thiopentone (5 mg/kg) followed by suxamethonium (1.5 mg/kg), both within 25 seconds, and Group B atracurium (0.5 mg/kg) followed by thiopentone (5 mg/kg) again both within 25 seconds. Tracheal intubation occurred after one minute in Group A and 2 minutes in Group B to allow for full paralysis. In Group A intra-ocular pressure did not alter significantly from baseline and the maximum increase was only 0.93 mmHg. The statistical type II error risk was consistently below 55% and all 95% confidence limits included negative values. Intra-ocular pressure in Group B was consistently lower than baseline (p less than 0.05) but with a longer induction-intubation interval. These results therefore provide valuable information about the 'balance of risks' when choosing a muscle relaxant for an inadequately starved patient with a penetrating eye injury.

Adolescent↗
PubMed1987

Abscess following cannulation of the radial artery.

Local abscess formation, septicaemia and median nerve palsy occurred as complications of radial artery cannulation in a 24-year-old man with malaria. The case is described and the nosocomial infection hazard of arterial cannulation is discussed.

Abscess↗
PubMed1987

Cardiac arrest in near-term pregnancy.

This case study emphasises the multiple factors that may be involved in the precipitation of electromechanical dissociation, which are compounded by additional problems that relate to pregnancy. It reinforces the value of the tracheal route for drug administration when a central vein is not cannulated and stresses the importance of posture and early consideration of Caesarean section in the pre-term gravid patient who has sustained a cardiac arrest.

Adolescent↗