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S L Matarasso

Publications and source records attributed to S L Matarasso.

24 records · Page 2Linked to original sources

Chemical face peels.

Application of caustic chemicals to improve cosmesis and reverse actinic damage has been used for centuries. Although still not an exact science, it was not until the latter part of this century that peeling became more systematized. The indications, patient selection, armamentarium, histology, comprehension of the mechanisms of action, and safety parameters of peels have only recently become more extensively defined. Phenol, when used in the Baker's formula, provides the most dramatic results but also holds the most potential for systemic complications. Ideally suited for fair-skinned women, a phenol peel can provide substantial improvement in rhytidosis and actinic damage. Although the results of medium-depth peels approach those of Baker's peels, they are not quite as profound. Use of TCA and the medium-depth peels has filled an important gap between deep and superficial peels, however. Also ideal for light complexions, this category of peels lightens pigmentary problems and improves rhytides with minimal potential for systemic toxicity; however, local complications, including scarring and pigmentary anomalies, should not be underestimated. [table: see text] Superficial peels do not effectively eradicate the ravages of time and sun, but when done repetitively, they do improve pigmentary irregularities and may improve some minor surface changes and thus impart a fresher appearance to facial skin. Although pigmentary changes can occur, superficial peels are relatively safe, and maximal results can be achieved with serial applications. Peels have been categorized by patient indications and the corresponding depth of peeling required for improvement (Table 4). The depth is determined in turn by a host of factors (Table 5). Neither the classification scheme nor the peel process should be viewed dogmatically. Patients will often benefit from the concurrent use of different skin preparations and wounding agents. Localized gradations can be achieved not only with occlusion but also by employing different solutions as well as different concentrations of the same solution and skin preparation. Selection of the appropriate technique relies on critical analysis of the skin defect one wishes to treat balanced against the risks of treatment. The final protocol should be individualized for the needs of each patient. Despite heightened public awareness of the harmful effects of ultraviolet radiation, actinically damaged skin is no longer a problem restricted to an older-patient population. Fueled by the lay press and practitioners, there is a growing patient demand for chemical peels. Chemical peels alone or combined with ancillary aesthetic procedures can provide a dramatic improvement in facial appearance. The potential for improved cosmesis is not without inherent risk, however.(ABSTRACT TRUNCATED AT 400 WORDS)

Chemexfoliation↗

The role of chemical peeling in the treatment of photodamaged skin.

Management of the aging face involves evaluation of the degree of solar elastosis, rhytidosis, and the structural changes associated with senescent skin. Chemical facial exfoliation is divided into deep, medium, and superficial based upon depth of penetration of the caustic agent used. Knowledge of the appropriate indications and technique are essential in obtaining optimal clinical results.

Chemexfoliation↗

A regional approach to patient selection and evaluation for liposuction.

Any area of the body where the deformity is due to regional excess fat and where there is overlying good skin tone is presumably amenable to body contouring by liposuction. It is an understandable temptation to attempt to remove large quantities of fat without major surgery and without noticeable scars. With experience, the surgeon will be able to estimate preoperatively the amount of fat that should be removed. However, liposuction is a procedure that requires conservatism because overzealous fat removal can generally leave unsightly permanent sequelae. Careful patient selection and proper identification of the correct indications of the technique are of paramount importance in achieving good aesthetic results and in avoiding complications. The ideal candidate is young, with good skin tone, moderate localized fatty deposits, and realistic expectations. There is certainly a wide range of patients who will benefit from the use of liposuction, and the average patient with less-than-ideal indications is more commonly encountered. The poor candidate is obese or has a significant deformity, poor skin tone, and, ironically, the most unrealistic expectations. Old age is not an absolute contraindication, although with increased age there is a concomitant decrease in elastic fibers, resulting in decreased capability to adapt a new contour. However, many patients "past their prime" will also have an acceptable cosmetic result and are particularly pleased with their changed, clothed silhouette. Appropriate patient selection, appreciation of the underlying anatomy, and judicious surgical technique are all essential for optimal results and patient satisfaction. Liposuction as described, either alone or as an adjunct to other procedures, allows for optimal aesthetic correction of figure faults due to adipose tissue.

Adipose Tissue↗

Zosteriform metastasis: case presentation and review of the literature.

In contrast to benign tumors, malignant tumors, by definition, are characterized by the potential of giving rise to metastases. Albeit infrequently, skin metastases do occur, and their clinical appearance varies over a wide morphologic spectrum. We present the case of a 65-year-old male with zosteriform metastasis secondary to bronchogenic adenocarcinoma. A review of cutaneous metastasis is presented with emphasis on dermatomal distribution and possible mechanisms of dissemination.

Adenocarcinoma↗

Nucleation-controlled aggregation of deoxyhemoglobin S. Effect of organic phosphates on the kinetics of aggregation of deoxyhemoglobin S in concentrated phosphate buffer.

The kinetics of the aggregatin of deoxyhemoglobin S in concentrated phosphate buffer were studied turbidimetrically in the presence of organic phosphates. The addition of inositol hexsphosphate shortened the delay time by 35-80%, the range depending on the hemoglobin concentration. The logarithmic plot of delay time versus hemoglobin concentration in 1.85 M potassium phosphate buffer, pH 7.34, showed a linear relationship with a slope (n value) of 2.5 +/- 0.14 in the absence of inositol hexaphosphate, while the slope was decreased to 2.1 in the presence of inositol hexaphosphate. The turbidity (A700) of aggregates per g deoxy Hb S was found to be lower in the presence of inositol hexaphosphate than in the absence of inositol hexaphosphate. The solubility of deoxy Hb S was decreased by inositol hexaphosphate. 2,3-Diphosphoglyceric acid also showed an effect similar to that of inositol hexaphosphate. However, if the pentacyclohexylammonium salt of diphosphoglyceric acid were used, the delay time was increased significantly. The opposite effect of the pentacyclohexylammonium salt of diphosphoglyceric acid on the delay time was found to be attributed to the anti-gelation effect of the pentacyclohexoxylammonium ion. The difference in the effect of inositol hexaphosphate and diphosphoglyceric acid on the delay time appears to be related to their effect on the solubility of deoxy Hb S.

Diphosphoglyceric Acids↗