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Biomedical subjects

S L Morganstern

Publications and source records attributed to S L Morganstern.

4 recordsLinked to original sources
PubMed1979

Malacoplakia of the bladder: efficacy of bethanechol chloride therapy.

Present evidence suggests that malacoplakia is the result of a functional defect in the mononuclear cells of the lesion caused by a deficiency of cyclic 3',5' guanosine monophosphate. This defect results in the impaired ability of the macrophage to release lysosomal enzymes necessary for the digestion of phagocytized bacteria. The persistent inflammatory reaction produces the characteristic granuloma of malacoplakia. Previous laboratory studies indicate that the phagocytic defect is reversible by cholinergic agonists, which led to the use of bethanechol chloride in the treatment of patients with malacoplakia. We report on 3 patients with vesical malacoplakia who were treated successfully with bethanechol chloride.

Adult↗
PubMed1977

Preureteric vena cava.

Preureteric vena cava is a rare congenital anomaly usually presenting clinically with hydronephrosis and an "S or fishhook" deformity of the ureter at the third or fourth lumbar vertebrae. Unusual presentations do occur and can lead to misdiagnoses. Herein such a case originally diagnosed as a ureteropelvic junction obstruction is presented and the embryology reviewed.

Adult↗
PubMed1976

Medical management of refractory hematuria in sickle-cell trait.

Hematuria secondary to sickle-cell trait has on occasion proved refractory to medical management. We have adopted a new six-drug regimen to deal with this difficult problem. Herein is reported our experience with this protocol in 2 patients. Our results have been excellent, with hematuria clearing within twenty-four hours. The drug regimen is used in an attempt to alter the conditions that are favorable for sickling in the renal medulla.

Acetazolamide↗