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Biomedical subjects

S L Oliver

Publications and source records attributed to S L Oliver.

7 recordsLinked to original sources

Molecular characterization of bovine enteric caliciviruses: a distinct third genogroup of noroviruses (Norwalk-like viruses) unlikely to be of risk to humans.

Bovine enteric caliciviruses (BoCVs) have been classified in the Norovirus (Norwalk-like virus) genus of the Caliciviridae, raising questions about zoonotic transmission and an animal reservoir for the human Norwalk-like viruses (NLVs), an important cause of nonbacterial gastroenteritis in humans. We examined the genetic relationship of human NLVs to BoCVs that were identified by using reverse transcription-PCR with primer pairs originally designed to detect human NLVs. Polymerase, capsid, and open reading frame 3 (ORF3) gene sequence analyses of BoCVs that were identified from 1976 to 2000 from throughout the United Kingdom showed that BoCVs formed a distinct third genogroup of closely related viruses distinct from the human genogroup I and II NLVs. Evidence was not obtained to support the concept that BoCVs are circulating in humans and pose a threat to human health.

Amino Acid Sequence↗

Isotropic mixing, sign discrimination, and sensitivity in solid-state wideline heteronuclear correlation experiments.

A variant of the solid-state wideline heteronuclear NMR correlation experiment is described which overcomes some of the drawbacks associated with the routine experiment. The modified experiment results in spectra which are sign-discriminated in the omega(1) dimension, but without the loss in sensitivity expected for a standard hypercomplex implementation. In favorable cases sensitivity enhancements over comparable routine experiments are obtained. As well as these advantages, the method retains the selectivity of modified WISE experiments proposed previously which give spectra containing correlations between directly bonded nuclei only.

Carbon Isotopes↗

Mood and lithium in drinking water.

To assess the possible relationship of lithium in the drinking water to some aspects of mental health, drinking water samples were collected from the homes of 384 individuals in Washington County, Md, who had been randomly selected for interview in a community mental health assessment program. The water was analyzed for lithium by atomic absorption spectrophotometry without knowledge of the interview results. The questionnaire contained the Lubin depression adjective check list, Center for Epidemiologic Studies depression and functioning scales, a general happiness question (Gurin), an aggression scale, and the Cantril ladder for self-rating of present status. In an area with low-to-moderate levels of lithium in the drinking water, there was no evidence to confirm earlier suggestions that the presence of lithium might be beneficial.

Adolescent↗

Dancing with angels.

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Attitude to Death↗