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S L Rybalko

Publications and source records attributed to S L Rybalko.

26 records · Page 2Linked to original sources
PubMedDate not supplied

[The mitogenic activity of the glycopolymers from Clavibacter (Corynebacterium) michiganense and Pseudomonas solanacearum].

A comparative study of the mitogenic activity of glycopolymers has shown that the activity of polysaccharides isolated from Clavibacter michiganense is higher than that of lipopolysaccharide of Escherichia coli, Pseudomonas solanacearum and mefenaminic acid (the synthetic mitogen). Lipid A and the core oligosaccharide fraction are established to be responsible for the mitogenic activity of the P. solanacearum lipopolysaccharide. O-specific chains and fractions of KDO-phosphates do not manifest the mitogenic activity.

Adjuvants, Immunologic↗
PubMedDate not supplied

[The use of carbon carriers for the immunoenzyme diagnosis of viral infections].

Carbon solid phase for enzyme-linked immunosorbent assay was proposed. This support can be used instead of polysterene plates because the following steps (carbon support incubate with specific and detective reagents) are implemented in arbitrary minimal capacities. The method was tested for detection of the virus antigens (hepatitis B, herpes simplex) and anti-viral (anti-adenovirus, anti-influenza virus) antibodies.

Adenovirus Infections, Human↗
PubMedDate not supplied

[The reproductive characteristics of human adenovirus type 2 in cultures of lymphoblastoid cells with B and T phenotypes].

A comparative characteristic of the reproduction process of type 2 human adenovirus in several lines of lymphoblastoid cells of B- and T-phenotype is presented. Formation of hexone and infectious virus in the cells of Jurkat, MT4, Raji lines was rather intensive and approached to that in the culture of the permissive epithelium cells Hep-2. These indices were much lower in the cultures of cells B 95-8 and MT4/BIII LBK which were chronically infected by VEB and HIV, accordingly and produced them that can evidence for the interference of Ad and VEB or Ad and HIV under superinfection of cells. Cells of SEM line possessing T-phenotype, were apparently semi-permissive for Ad h2, though the low almost unchanged content of hexone and infectious virus remains in them for a rather long time: about 15 days. Thus, obtained data within analyzed series of experiments expand the present ideas about lymphotropicity of Ad as their important property realized at the level of cell and infected macroorganism.

Adenoviruses, Human↗
PubMedDate not supplied

[The biological activity of a lipopolysaccharide from Ralstonia solanacearum ICMP 7859 and of its modified derivative].

Coordinational compound of the Ralstonia solanacearum ICMP 7859 lipopolysaccharide (LPS) with germanium was obtained. The derivative has lost to considerable extent its toxicity (as compared to the initial substance) but preserves immunomodulating activity, interferon-inducing one in particular. Lipid A modification has led to complete loss of interferon-inducing activity. Apparently, phosphate at C4' GlcN II can be responsible for interferon-inducing activity of lipid A, while carboxylic groups of core oligosaccharide or 0-specific polysaccharide, are responsible for that in native molecule of LPS.

Cytopathogenic Effect, Viral↗