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S L Weinberg

Publications and source records attributed to S L Weinberg.

16 recordsLinked to original sources
PubMed1978

Internal medicine.

Explore the source record for details and available documents.

Intensive Care Units↗
PubMed1978

Intermediate coronary care. Observations on the validity of the concept.

Recognition of significant mortality among hospitalized patients with myocardial infarction after dismissal from the coronary care unit (CCU) has led to the introduction of the intermediate coronary care unit (ICCU). It had been hoped that protracted monitoring during the convalescent phase of acute myocardial infarction might prevent sudden death, as in the CCU. Study of patterns of survival among 1,361 patients with acute myocardial infarction included 814 patients treated prior to the establishment of an ICCU and 557 managed in such a unit. Analysis of the two groups (including such high-risk factors as congestive heart failure, tachyarrhythmias, previous infarction, cardiac enlargement, and other unfavorable manifestations) failed to reveal a reduction in mortality after introduction of the ICCU. Thus, the value of the ICCU cannot be demonstrated in terms of mortality. Other benefits of the ICCU are projected, which include more sophisticated evaluation of the patient prior to discharge from the hospital and expanded opportunities for education of patients. A definite role of the ICCU in the total management of the patient with coronary arterial disease is postulated.

Coronary Care Units↗
PubMed1977

Ureteral function. IV. The urometrogram at increased urine output.

In this study the shape of the urometrogram or ureteral pressure pulse is evaluated as a function of urine output. Using a simultaneous monitoring technique, the urometrogram, spurt volume, and wave speed, as well as various aspects of wave geometry, have been studied on dogs with explanted bladders during various stages of urine output. The qualitative shape of the urometrogram is discussed for urine flows ranging from less than 0.01 ml per min to about 6 ml per min. An explanation of the shape of the urometrogram is presented and shown to be related to urine output and to length of the bolus. Preliminary experiments using mannitol, Lasix, Hypaque, and saline were all shown to induce similar changes in the shape of the urometrogram; however, the rate at which the changes occur was a function of the specific drug.

Animals↗
PubMed1976

Natural history six years after acute myocardial infarction. Is there a low-risk group?

One hundred fifty-four survivors of acute myocardial infarction were observed for six years. Patients with anterior lesions had increased mortality in the acute phase of infarction, a trend not sustained during the long-term follow-up period. Recurrent myocardial infarction and intraventricular conduction disturbances were associated with relatively high short-term and long-term mortality. Four groups were defined. The high-risk group had congestive heart failure, major bundle-branch block, previous myocardial infarction, ventricular tachyarrhythmias, or second- or third-degree atrioventricular block. The low-risk group had none of these stigmata. Each category was divided into those under and over the age of 60. Only patients in the low-risk group, over 60 years of age, (24 percent) had a six-year survival comparable to the standard actuarial projections. Thus, 74 percent of the survivors of the acute phase of infarction had a six-year mortality far in excess of the general population. Some were particularly vulnerable during the first year. These findings may warrant reappraisal of the indications for diagnostic and surgical approaches to managing patients after myocardial infarction.

Acute Disease↗
PubMed1976

Ureteral function. III. The catheter and the geometry of the ureter.

The geometry of a canine ureter with and without the presence of an indwelling catheter has been studied after in vivo freezing and sectioning. Changes in ureteral cross-section were observed as catheter size was increased from about 2 Fr. through 6 Fr. using a new microphotographic procedure. These preliminary results indicate direct contact between the ureteral wall and catheter during ureteral contraction, relaxation, and inactivity. In the region of a urine bolus, an open lumen could be clearly observed. The shape of the lumen appears to depend on the bolus volume, the size of the catheter, and local muscular characteristics of the ureteral wall. In the absence of a catheter, the lumen appears to vary between a totally collapsed configuration and an almost circular shape.

Animals↗
PubMed1975

Ambulatory monitoring of arrhythmias.

Currently available instrumentation provides the capability of ambulatory electrocardiographic monitoring. A considerable body of literature has developed since the late 1950s which defines an important role for this technique in clinical practice. The use of ambulatory monitoring may ultimately prove as useful in the diagnosis and treatment of occult arrhythmias during activity as monitoring has been during acute phases of myocardial infarction.

Adult↗
PubMed1975

Ureteral function. II. The ureteral catheter and the urometrogram.

The relationship between the urometrogram and the indwelling ureteral catheter was studied on female dogs having surgically explanted bladders. A new monitoring technique was employed which allowed for simultaneous recording of urometrogram, spurt volume, wave speed, and wave geometry for each peristaltic wave. The caliber of the catheter was shown to influence both contractile amplitude and basal pressure level of the ureter. In one case, an increase in catheter size from 3.6 Fr. to 5 Fr. resulted in a 5-mm Hg rise in basal pressure with a simultaneous increase of 35 mm Hg in peak pressure amplitude. In addition, it was also shown that in dog ureters, catheters as small as 3.6 Fr. may result in elevated pressure levels. Based on experimental observations and an understanding of the passive and contractile characteristics of ureteral smooth muscle, a new model ofthe urometrogram is presented which is based on a contact pressure between the ureteral wall and catheter.

Animals↗
PubMedDate not supplied

Observations on ambulatory electrocardiographic monitoring in clinical practice.

Holter monitoring is a practical technique for determining rate, rhythm, contour, and conduction changes in the electrocardiogram of the ambulatory patient. This kind of information may be of great clinical importance in coronary artery disease with or without myocardial infarction, in patients with permanent pacemakers, in the presence of central nervous system symptoms, and perhaps in patients with chronic obstructive pulmonary disease. Correlating ambulatory electrocardiographic findings in patients with these diseases and syndromes provides insight into the severity of the process involved. It may also define the response to therapy and to specific social and work situations. Present instrumentation, although reasonably effective, may be considered in an early developmental stage. Future progress in terms of miniaturization, automatic patient warning systems, and activation of central recording units, may further broaden the implications for ambulatory electrocardiographic monitoring. The scope of these observations and the variety of unsuspected rhythm and contour abnormalities defined may ultimately rival the information gained in monitored hospitalized patients. It is hoped that this information will have an impact on the therapy of the ambulatory patient comparable to that which coronary-care unit monitoring has had on the hospitalized patient with acute myocardial infarction.

Adult↗
PubMedDate not supplied

The clinical importance of coronary arteriography after myocardial infarction.

An analysis of 80 patients who had elective coronary arteriography within 6 months after hospital dismissal for acute myocardial infarction showed that approximately two-thirds had multivessel coronary disease. The study is consistent with others reported in the recent literature in suggesting that most patients who survive myocardial infarction have multivessel disease. High early and late post-myocardial infarction mortality is comparable to that described for patients with two- and three-vessel occlusive disease. Knowledge of specific coronary anatomy and left ventricular function is critical in assessing post-myocardial infarction prognosis. This information is also important in defining optimal medical or surgical treatment. Unfortunately, the severity of the subjective clinical syndrome does not correlate well with the degree of anatomic findings or the prognosis. Properly selected surgical intervention may be one approach to modifying the high post-myocardial infarction mortality, which has not changed materially in the past several decades.

Adult↗