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Biomedical subjects

S L Weissman

Publications and source records attributed to S L Weissman.

At least 19 recordsLinked to original sources
PubMed1982

Osteoarthritis of the hip and fracture of the proximal end of the femur.

The purpose of this investigation was to verify a long-standing clinical observation that patients with fracture of the proximal end of the femur have less evidence of osteoarthritic changes in their hip joints than would have been expected in patients of similar age groups. The radiographs of 342 patients with fractures and those of 157 controls were examined. The statistical results gave uncontroversial evidence that the incidence of osteoarthritic joints was lower in the fracture group. The difference was even greater with severe osteoarthritic changes. This suggests that patients with osteoarthritis have a "better quality" of bone. They are less likely to be suffering from osteoporosis and less liable to fractures of the proximal end of the femur.

Age Factors↗
PubMed1981

The development of the normal infantile hip as expressed by radiological measurements.

Acetabular and centre edge angles were measured on normal radiographs of 164 children (328 hips) aged from three months to five years. Using regression and correlation analysis, mathematical formulae were derived which allow the calculation of the normal acetabular and centre edge angles for a given age. The relationship between age, acetabular angle and centre edge angle was studied.

Acetabulum↗
PubMed1980

Skeletal findings in human neutrolethyrism. Is there a human osteolathyrism?

In a review of the roentgenological files of 22 patients suffering from spastic paraplegia due to neurolathyrism, 3 patients were found to present abnormal skeletal findings. 2 patients showed absence of union of the secondary ossification centres of the iliac crests, the ischial tuberosities and the vertebral bodies. Their age at the time of ingestion of poisonous Lathyrus sativus plants was 19 and 20 years. The 3rd patient had bowing and thickening of his right femoral shaft. He was 22 years old at the time of poisoning. These findings which are similar to those found in experimental osteolathyrism have never been described in clinical neurolathyrism. They are of a nature to throw some doubt on the correctness of the currently prevailing concept of sharp distinction between these two pathological entities.

Bone Diseases↗
PubMed1979

[Treatment of fractures of the femoral neck by primary femoral prosthesis (author's transl)].

The authors have reviewed 230 case of fractures of the femoral neck treated by primary femoral prosthesis. The mortality was 12,6 p. 100 during the first three post operative months, and 16,5 p. 100 after three additional months. The infection rate was 13,9 p. 100, 4,7 p. 100 of the cases being severely infected. The postero lateral approach was more favourable than the antero-lateral approach. Late results were studied on 142 cases. The average follow-up was 4 years. The clinical results were closely dependent on the radiological appearance. When the prosthesis progressively penetrated into the femoral medullary canal incapacitating pain was always present. It is concluded that the use of cement may improve the results in a number of cases.

Aged↗
PubMed1979

Growth and development of congenitally dislocated hips reduced in early infancy.

We determined the acetabular angles, center-edge angles, comprehensive quotients, and Shenton's lines from sequential roentgenograms of thirty-seven children with congenitally dislocated hips treated by closed non-manipulative reduction in early infancy. The values were compared with those obtained from roentgenograms of 164 normal children who ranged in age from three months to five years and of forty-three adolescents and adults. The hip recovering from congenital dislocation developed similarly to the normal hip but differed in that it showed a greater rate of decrease of the acetabular angle and an increase in the center-edge angle. Significant development after the age of five years still was manifested in the reduced hips.

Acetabulum↗
PubMed1978

An evaluation of surgical and conservative treatment of fractures of the ankle in 200 patients.

The longterm results of surgical and conservative treatment in two almost identical groups of patients with fractures of the ankle have been analyzed. The results were better after conservative treatment; delayed operation and repeated manipulations were found to be the main reason for the poorer postoperative results, especially in elderly osteoporotic patients. The damage consequent to repeated manipulations, the difficulties resulting from delaying operation, and the advantages of early open reduction are discussed. It may be that under certain conditions of unavoidable delay, a mild residual displacement should be accepted rather than repeated manipulation and delayed open reduction. It is concluded that, when indicated, operations should be performed as early as possible after injury, probably giving the best end results as evidenced by the preliminary findings of a prospective study currently under way.

Adolescent↗
PubMed1978

The clinical use of combined xenografts of bone and autologous red marrow. A preliminary report.

The beneficial effect upon osteogenesis of imprenating bone grafts with autologous red marrow is well documented. The experimental findings reported in a previous paper suggested that prepared xenograft bone might provide a good medium for osteogenesis by marrow cells. This paper is a preliminary report of the first clinical attempt to use xenografts of bone combined with autologous red marrow. Kiel bone, which was found the most suitable, was impregnated with marrow aspirated from the iliac crest and, apart from one case of infection, gave excellent results in twenty-eight patients under conditions covering a wide range of indications for bone grafting. Further trials should allow a more valid assessment.

Adolescent↗
PubMed1978

Joint changes after overuse and peak overloading of rabbit knees in vivo.

The effect of overuse and overuse combined with axial peak overloading on the knee joints of living rabbits has been investigated. A specially constructed apparatus was used for this purpose. Physical and biochemical changes are reported and include: 1. Early and progressive damage to the articular cartilage surface shown by the scanning electron microscope. 2. The presence of an increased amount of prostaglandin E in the synovial fluid. 3. A reduction of cyclic 3'--5' monophosphate in the subchondral bone. 4. Late changes which were consistent with osteoarthritis. These changes were found only in the joints subjected to simultaneous overuse and peak overloading. The results suggest that: 1. Cartilage damage and chemical changes in the subchondral bone are simultaneous and are both responsible for eventual degenerative changes. 2. Frictional overuse alone does not seem to be responsible for the production of oesteoarthritis.

Animals↗
PubMed1977

Recurrent dislocation of the head of the radius.

Traumatic dislocation of the radius at the elbow may be more common than previously appreciated. It may not be diagnosed, or may belatedly be diagnosed as a congenital dislocation of the radial head. Recurrent dislocation does not seem to have been previously reported in the literature.

Adult↗