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Biomedical subjects

S L Yu

Publications and source records attributed to S L Yu.

66 records · Page 4Linked to original sources
PubMed1983

Esophageal cancer in migrants from high- or low-risk areas in China.

Death rates from esophageal cancer among migrant and indigenous populations were investigated in three areas in Hubei Province, China. The migrants were from Henan Province. Some came from Xichuam county where esophageal cancer is common and some from Shangchew Prefecture where the disease is less common. Death rates for the migrants moving from high risk to low risk areas over 10 years remained at a high level whereas migrants who have moved from low risk areas to low risk areas for periods in excess of 20 years have remained at a low level. That a small number of chickens raised by migrants from a high risk area developed gullet cancer would suggest the involvement of a traditional dietary habit and an associated carcinogen.

Age Factors↗
PubMed1981

Studies on the phenomenon of latent propagated sensation along the channels. I. The discovery of a latent PSC and a preliminary study of its skin electrical conductance.

By combining electrical impulse stimuli with mechanical ones, we are able to trace out a new line of feeling, coincident with the classical channel course. Impulse stimulation was carried out at the Jing point of the Large Intestine or Stomach channel, namely Shangyan or Lidui. With a small rubber nipple, light taps were applied on the skin along the lines perpendicular to the channel and crossing over the acupuncture points; a specific propagational numb feeling at the points of the channel could be found. By linking up these points of specific feeling, an imaginary line which is exactly the classical Large Intestine or Stomach channel can be traced out. This line is called the "latent propagational sensation line along the channels" because, unless through tapping, no prominent sensation of propagation could be felt. Employing an impulsive electrical generator and an all-wave commutating circuit linked to a micro-ammeter, the skin conductance was measured over the latent PSC of the Large Intestine channel lying between the wrist and 5 cm above the elbow joint. Results were compared to those locations of 1 cm apart from the channel course, i.e. the control sites devoid of acupuncture points or channels. At most acupuncture points or any site of the channel course on all of the 10 subjects under examination, there was greater electrical conductance maxima than there was at control sites. This fact indicates that not only the acupuncture points, but the entire course of latent PSC are also of higher electrical conductance.

Acupuncture Therapy↗
PubMedDate not supplied

Organization of HIV-1 pol is critical for Pol polyprotein processing.

The HIV pol sequentially encodes protease (PR), reverse transcriptase (RT), and integrase (IN) from the 5'-3' direction. We explored the significance of this gene arrangement. All six possible gene dispositions were examined. In two situations where PR was removed from the leading place and no two genes were in their original location, viral polyprotein processing was abolished. Processing of the polyprotein did not occur when IN was translocated to the front of PR-RT. However, in the following two arrangements, the polyprotein was processed but only at specific sites. First, PR remained in the leading position while the locations of RT and IN were exchanged; viral polyprotein was processed at a site between the upstream transframe peptide (TF) and PR. Second, PR was placed after RT-IN and located at the distal end of Pol. Processing occurred only at the created junction between TF and RT. These results indicated that cleavage after TF occurred autocatalytically but did not proceed to a second site, which needed an extraneous PR for trans-action. Therefore, arranging Pol in the order of PR-RT-IN warrants the streamline processing of the polyprotein once the autocleavage is initiated.

Amino Acid Sequence↗
PubMedDate not supplied

Brief report: speed of information processing in children with insulin-dependent diabetes mellitus.

OBJECTIVE: To determine whether children with insulin-dependent diabetes mellitus (IDDM) process information more slowly than children who do not have diabetes. METHODS: We tested 31 children with early onset and longer duration of IDDM, 35 with later onset and briefer duration of IDDM, and 36 comparison children without diabetes. They were administered five tasks requiring rapid responding that assessed a range of cognitive processes. RESULTS: On most tasks, children in the three groups were quite similar in the accuracy and speed of performance. Furthermore, for children in the diabetic groups, disease-related variables were unrelated to accuracy and speed of performance. CONCLUSIONS: The results suggest that children with IDDM do not have a pervasive deficit in speed of information processing, although more circumscribed deficits in processing speed are possible.

Adolescent↗