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Biomedical subjects

S Langenberg

Publications and source records attributed to S Langenberg.

3 recordsLinked to original sources

[Development of a database system for multicentric ENT tumor documentation].

BACKGROUND: Multicentric clinical studies have a great impact on progress in diagnostics and therapy in oncology. However, multicentric retrospective clinical trials require a common documentation standard. METHODS: A network enabled tumor documentation program based on a relational database system was developed for the management of multicentric clinical studies. This system is designed for the documentation of treatment and follow-up. CONCLUSION: The use of a computer-supported documentation system minimizes documentation effort and error frequency. However, communication with cancer registries is still an unsolved problem.

Clinical Trials as Topic↗

[Influence of comorbidity on the prognosis of squamous cell carcinoma in the head and neck].

BACKGROUND: The influence of comorbidity on the healing process and the prognosis of patients with carcinoma of the head and neck region undergoing surgical treatment is not clear. PATIENTS AND METHODS: In a retrospective study we examined the influence of coexistent diseases in 203 patients, hospitalized for curative surgical treatment. Findings on admission, supplemented by medical, anaesthesiological and neurological assessments, helped to form two subgroups: one of patients with minimal comorbidity (n = 135) and one with high comorbidity (n = 68). Subsequently the duration of hospitalization, incidence of complications, disease-free interval and survival was statistically compared. RESULTS: The duration of hospitalization, the incidence and degree of complications, the disease-free interval and the overall survival differed significantly, showing better results in the group with low comorbidity. CONCLUSION: Coexistent, mainly medical, diseases had a significant influence on the results of surgical treatment and prognosis of head and neck cancer.

Carcinoma, Squamous Cell↗

Practical aspects to realize data transfer between a patient administration mastersystem and clinical subsystems using ProtoGen/HL7.

At the Medizinische Einrichtungen Bonn the module IS-H of SAP R/3 is used for patient administration. All clinical subsystems will be provided with patient data using HL7 2.3 messages. These messages are generated from HCM messages a proprietary format of IS-H by means of a communication server. Interface application for subsystems which are not capable of processing HL7 messages are written using the open source C++ class library ProtoGen/HL7. First experiences and remaining problems are discussed.

Data Collection↗