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Biomedical subjects

S Largueche

Publications and source records attributed to S Largueche.

At least 19 recordsLinked to original sources
PubMed1988

[Perineal gangrene secondary to abscesses of the anal margin. Apropos of 9 cases].

Of 9 patients with perineal gangrene secondary to abscess of anal margin, 7 presented deficiency states. Diagnosis was established after an average of 7.4 days following onset of signs, although the clinical picture was obvious and the lesions extended beyond the perineum towards the genital organs, buttocks or thigh. Essential therapy consisted of antibiotic cover, immediate and repeated surgical excision (average number of operations per patient = 6) and stools bypass by colostomy for severe perineal lesions. This resolutely aggressive treatment reduced mortality of this reputedly serious affection to 2 cases (22%), but morbidity was high and a perineoplasty was necessary in a third of the patients.

Abscess↗
PubMed1982

[Agenesis of the gallbladder. Comments on physiopathology and diagnosis. Apropos of 2 cases].

Initially a simple anatomical curiosity discovered at operation or autopsy, agenesis of the ball bladder has now, and despite its rarity, become of the greatest interest from a pathogenic, physiopathological and diagnostic standpoint. Embryogenesis explains that this a developmental abnormality affecting the hepatic diverticulum which is probably of genetic origin, hence its frequent association with other malformations and the hereditary nature of the condition. The usual finding of a syndrome of blockage of the sphincter of Oddi with dilatation of the common bile duct raises the problem of synergism between the sphincter of Oddi and the gall bladder. The discovery of lithiasis of the hepatic and common bile ducts in agenesis of the gall bladder leads to discussion of the reality of organ lithiasis or the role of the distended wall of the common duct. Cholecystography and echotomography would appear to be the two techniques of investigation to be recommended preoperatively in order to increase support for the presumptive diagnosis once disorders affecting neighbouring structures have been eliminated. The definite diagnosis is made peroperatively by manual exploration, peroperative cholangiography or even coeliac arteriography during the operation. The indication for surgery is based upon clinical symptomatology. This does not treat the agenesis but the associated lesions which are its complications, in particular: lithiasis the common duct, sphincter of Oddi block syndrome and dilatation of the common duct.

Abnormalities, Multiple↗
PubMed1980

[Dacron tulle prosthesis and biological glue in the surgical treatment of incisional hernias (author's transl)].

In repair of incisional hernias the authors use Dacron tulle material for less than peritoneal sac reinforcement prosthesis greater than (PSRP)--a method which prevents recurrences whether or not the abdominal wall is badly damaged. A biological glue (n-butyl-cyanoacrylate monomer) in many cases avoids direct or indirect suture of the patch). In practice, there are two types of PSRP. In one type, the gap in the abdominal wall is small and can be sutured, and the peritoneal Dacron tulle patch is a mere adjunct to parietal synthesis. In the other type, the medial, lateral or peripheral eventration is extensive or recurrent, and parietal synthesis is impossible. A piece of Dacron tulle of very large size is then inserted without any glue or transfixing sutures to help solve mechanical and pathophysiological problems.

Adhesives↗