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Biomedical subjects

S Latinović

Publications and source records attributed to S Latinović.

9 recordsLinked to original sources

[Changes in ocular refraction after tamponade with silicone oil].

In order to study refractive changes caused by a intravitreal silicone oil injection we retrospectively analyzed 25 eyes after vitreoretinal surgery combined with silicone oil tamponade. In all cases the postoperative visual acuity was 0.1 or better. Mean difference in refraction after silicone oil tamponade in phakic eyes was +5.07 Dsph (+2.0 to +8.0 Dsph). Mean refractive change in the aphakic silicone oil filled eyes was - 6.63 Dsph (-4.0 to -9.0 Dsph). Silicone oil extraction induced a greater refractive change (myopic shift, mean -5.57 Dsph) than silicone oil injection. After silicone oil extraction from the aphakic eyes refractive changes (shift towards hypermetropia, mean +5.86 Dsph) were less manifest than after silicone oil injection. The disparity could be explained by eye elongation after cerclage performed during primary vitreoretinal surgery.

Humans↗

[Treatment of retinal detachment using pneumatic retinopexy].

A series of 46 eyes with idiopathic rhegmatogenous retinal detachment, treated by pneumatic retinopexy has been reviewed. Of 46 eyes 8 were aphakic and 3 pseudophakic. In 4 eyes proliferative vitreoretinopathy was preoperatively present. Anatomic success was achieved in 59% of cases after follow-up of 6-26 months. With additional operations (conventional and/or vitrectomy) anatomical success rate was increased to 98%.

Adult↗

[Diabetic retinopathy and other complications of diabetes mellitus].

The paper reviews the results of a ten-year follow up conducted in 140 diabetic patients at the Ophthalmology Clinic in Novi Sad. We analysed the number of the cases and ratios between diabetic retinopathy and other complications in eyes and other organs. Apart from retinopathy among eye diseases the most frequent was hypertonic fundus in 20%, cataract in 17% of the eyes and occlusive conditions in the retinal blood vessels in 2.6%. In the whole group only 8% of the examined eyes had no changes. Complications develop in 70% of diabetics with retinopathy and 48% of those without retinopathy. Nephropathy was found in 18% of diabetics with retinopathy and 13% of those without it. Macroangiopathy of the brain, heart and peripheral blood vessels was found in lower percentage but more frequently in diabetics with retinopathy.

Adult↗

[Dry eye as a therapeutic problem].

Effects of substitution therapy was investigated in 42 patients having the dry eye syndrome associated with systemic diseases of connective tissues (systemic lupus, Sjögren's syndrome, etc). Artificial tears were applied: Liquifilm sol, Hydroxypropyl methylcellulose 0.3% (HPMC) and Ocutal sol. After the one-month application of each preparation, mean values of Schirmer's test were approximately identical and the differences were not statistically significant (4.5 +/- 3.5; 4.95 +/- 4.4; 4.01 +/- 3.6), differing slightly from mean values of Schirmer's test prior to the treatment (4.4 +/- 3.4; 3.9 +/- 2.5). The lacrimal secretion did not increase after the administration of the above therapy. The therapy with artificial tears resulted in the improvement of subjective complaints (scratching, dryness and burning sensation) in 65% of cases treated with Liquifilm sol, in 69% upon the administration of HMPC 0.3% and in 60% after the application of Ocutal sol.

Adult↗

[The mechanism of cholinergic effects on lowering intraocular pressure].

The relationship between vasomotoric activity and blood vessel permeability was studied in the course of discovering the ocular hypotonising mechanism of cholinergic drug activity (pilocarpin and carbamylcholin). The authors found, in experimental conditions, that the vasomotoric activity (vasodilatation) of the two cholinergic drugs is expressed in the increased permeability of the blood-aqueour barrier. In the presence of an elevated extracirculatory pressure (IOP), as in glaucoma, vasodilatation under the influence of cholinergic drugs, is converted to passive vasoconstriction which leads to reduced aqueous humor production. Carbamilcholin reduces aqueous humor production in a greater extent than pilocarpin.

Animals↗

[Modern microsurgery of the eye].

On the basis of obtained results on the University Eye Clinic of Novi Sad, the modern aspects of the most frequent microsurgical operations in ophthalmology are presented. Cataract operations with endocapsular implantation of IOL result in improvement of visual function and daily activities in 98% of patients. Vitreoretinal surgery leads anatomical and functional improvement in 50% to 85% of all cases in correlation with pathology. Different laser microsurgical techniques are used in vascular retinal diseases, corneal refractive surgery, prevention and treatment of glaucoma, secondary cataract treatment, and treatment of diabetic retinopathy.

Cataract Extraction↗