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Biomedical subjects

S Lenzi

Publications and source records attributed to S Lenzi.

At least 73 records · Page 4Linked to original sources

[Renal control of acid-base equilibrium during dyslipidemia].

Possible correlations between lipid metabolism and hydroelectrolytic and acid base balances were studied in pathological conditions. For this purpose 24 patients with essential dyslipidaemia without renal or hepatic disease, and 47 patients with varying disease conditions, 25 with profound alterations in the lipid balance, 22 with plasmatic lipid fractions completely normal, were studied. In cases of essential hyperlipidaemia, alongside the profound changes in the lipid complement, no significant alterations in plasma pH were observed; by contrast other cases frequently showed an upset acid base balance with or without changes in the lipid picture. Urinary determinations suggested different conclusions. The most important aspect was the observation in most cases of essential dyslipidaemia and in certain cases of secondary dyslipaemia, of paradoxical aciduria, namely aciduria of much greater extent than might have been expected on the basis of plasma pH value.

Acid-Base Equilibrium↗

[Changes in myocardial metabolism during atrial pacing and catecholamine stimulation in normal subjects and patients with angina].

5 patients with angina had their threshold for angina evaluated by atrial pacing and by stimulation with catecholamine (dopamine). The authors then studied the metabolic changes induced by the two types of anginogenic load (AP and D-test) applied successively, and compared them with the post-ergometry ECG changes (lowering of the ST segment by at least 2 mm) and the findings on coronary arteriography (complete obstruction of at least 75% stenosis of a major branch vessel). The metabolic measurements were controlled against those of 5 normal subjects after standard ergometry. In the patients with angina, the AP test led to a constantly negative value for %. L. By contrast, the values of D(a-v)c and % O2 which were reduced in the normals, as indirect evidence of an increased coronary flow, remained practically static. During the dopamine infusion, although the % L was reduced, it remained essentially positive, while the D(a-v)c and % O2 were consistantly lowered.

Adult↗

[Evaluation of the changes in some laboratory parameters in liver disease patients treated with Toxepasi Complex].

Toxepasi Complex (UDPG, glutathione and vitamin B12) was administered to patients with aggressive chronic hepatitis and a second group with severe cirrhosis. Changes in laboratory enzymological data indicative of the overall extent of liver damage due to cell necrosis, cholostasis and impairment of protein synthesis were evaluated. Decreases tending to normalisation were noted two weeks after the commencement of treatment, particularly in the first group. The results suggest that the complex may be usefully employed in the management of aggressive chronic hepatitis and cirrhosis of the liver.

Adolescent↗