Biomedical subjects

S Lo Duca

Publications and source records attributed to S Lo Duca.

2 recordsLinked to original sources

PubMed1987

Effects of mesoglycan sulfate on the arterial elastic module.

Ten patients with peripheral obstructive arterial disease (POAD) in stages I and II according to Leriche-Fontaine, were subjected to therapy with mesoglycan sulfate (60 mg/day for twenty days), to evaluate the effect of the drug on the elastic module of the arterial wall. The wall elasticity was deduced from some Doppler velocitographic indices (arterial dynamics index, resistance index, perfusion pressure index, tibial distensibility index); from the analysis of systolic, protodiastolic, and end diastolic velocity variations; and from computerized analysis of the Doppler sound spectrum. The results show a significant improvement of arterial wall elasticity, which suggests a rational use for the drug in the initial stages of peripheral obstructive arterial disease.

Arterial Occlusive Diseases↗

PubMed1985

[Hemorheological changes during exercise].

It is now necessary to study the macro- and microcirculatory modifications of the organism following the stress. We have devoted our attention to the hemorheological parameters, which have been evaluated in a group of ten sedentary subjects, of fourteen athletes under twenty years of age, and of ten subjects whose age was over thirty, who carry on physical unbroken performance. We have evaluated the modifications of total blood viscosity and of red blood cell deformability after an ergometric test. Our results show that the hemorheological pattern gets worse after strenuous muscular exercise; moreover, the advancing age gets worse the hyperviscosity response. The pathophysiological mechanism which causes the hemorheological disorder is yet unknown, so it is clear the importance of studying the hemorheological balance in order to clarify the pathophysiology of stressed muscular function.

Adult↗