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S Lymberopoulos

Publications and source records attributed to S Lymberopoulos.

At least 19 recordsLinked to original sources
PubMed1992

[The permanent endourethral prosthesis (Wallstent) for the treatment of posterior urethral strictures].

We present our experience with the self-expanding urethral endoprosthesis Wallstent for the treatment of recurrent posterior urethral strictures. The stent is made of a surgical-grade stainless steel alloy wire, woven into braided mesh and shaped to a tubular form. It was originally developed for use in endovascular stenoses. Immediately before implantation of the stent an internal urethrotomy with subsequent urethral dilatation is done. So far, 23 patients have been treated by this new technique of therapy, with follow-up periods of up to 25 months (mean 16.8 months). The endoprosthesis has been tolerated very well by all patients. Successful treatment of the strictures is confirmed by the physiological uroflow obtained and the absence of residual urine after emptying of the bladder. We have seen no recurrences of stricture. After 6 months, urethroscopic control examination demonstrates complete epithelialization of the urethral stent. One year after implantation the endoprosthesis is completely incorporated. The original diameter of 21.5 Charr is maintained, which allows subsequent transurethral endoscopic manipulation if necessary. Our encouraging results so far give reason to hope that this is a simple, safe and recurrence-free treatment for posterior strictures of the urethra.

Adult↗
PubMed1991

[Endovesical antireflux plastic surgery. Original technique].

The authors present a technique of endovesical transposition of the urethra with orthotopic reimplantation of latter. This very effective technique is simple. In addition, it allows secondary catheterization and reduces post-operative complications.

Adolescent↗
PubMed1991

[Sigmoid neobladder].

Explore the source record for details and available documents.

Carcinoma, Transitional Cell↗
PubMed1979

Morphologic and cell kinetic investigations of the spleen after repeated in situ freezing of liver and kidney.

In order to evaluate a possible primary or secondary immunologic response of the spleen after single or repeated in situ freezing of parenchymal organs such as liver and kidney within a four week period, light microscopic and cell kinetic investigations with tritiated thymidine were performed on spleens of non-germfree rats. Sham operations served as controls. The sham operations did not induce any significant morphological or cell kinetic changes in the splenic white pulp. After cryolesions were produced in the liver and kidney, the percentages of activated germinal centers, labeled germinal center cells, and cells in the perifollicular area of the lymphatic mantle and marginal zones increased, with maxima during the first 3 days. The investigations show that the cellular reaction of the spleen starts earlier and is more prominent after repeated in situ freezing than after a single cryolesion. These findings point to an immunologic response of the anamnestic type, and correspond to results after repeated freezing of normal and malignant tissue of the urogenital tract. These cell kinetic results are important in the evaluation of further immunologic studies involving the cryotherapy of malignant tissues.

Animals↗
PubMed1978

[Morphologic changes of the renal arteries following instrumental compression (author's transl)].

In the present work, light-microscopic changes in the renal arteries of the rabbit following instrumental compression for specific intervals are described: 1. Compression led to necrosis of whole layers of the vascular walls, which could already be observed under the light microscope after 3 h.--2. The degree of wall necrosis depends only on the pressure of the clamp: not on the duration.--3. Experience shows that, independent of the type of clamp, there is complete regeneration of the adventitia and media by the fourth postoperative week.--4. In all vessels, the residual effect is a 2--5 layer proliferation of the intima that extends over the entire clamped area for 4--8 weeks postoperatively.--5. In 2 out of 80 renal arteries, arterial thromboses developed.

Animals↗
PubMed1977

[Morphological findings on the brain of rats after local freezing (author's transl)].

In continuation of our investigations of the wound healing process after cryonecrosis in the liver, kidney, spleen and stomach, the wound healing in the brain was studied under the same condition. Through a trepanation of about 3 mm diameter, the cortex of the parietal region of the cerebrum was frozen by a cryoprobe applied directly through the intact dura mater (-196degreesC/30s). The animals were killed at definite time intervals between 12 h and 21 days after freezing. Twelve hours after freezing, the necrosis of the brain cortex is complete. It extends wedgeshaped into the subcortical white matter. The central parts of the necrosis become colliquative and are demarcted by leucocytes. Two days after freezing, the necrotic area is almost totally invaded by leucocytes. Three days p.op. the brain wound is infiltrated by microglial cells, later on the mesenchymal cell proliferation extends to the meninges. There is new capillary formation and partially a wall like proliferation of the perivascular connective tissue cells. Ten days and later, an uni- or multiloculated pseudocyst develops, which can be considered as the final stage of the reparative wound healing of the cryonecrosis. Similar as in the other investigated organs (liver, kidneys, spleen) these investigations underline the rapid wound healing of the cryonecrosis in the brain. The advantages of cryosurgical manipulations with the well known good wound healing process of other organs, justifies therefore the short term tissue freezing on the cerebrum.

Animals↗
PubMed1976

Wound healing of the brain of rats after cryonecrosis. Autoradiographic investigations with 3H-thymidine.

Histologic and autoradiographic studies were performed to investigate the cellular reactions during wound healing of the brain of rats after cryonecrosis. A parietal lobe was frozen for 30 s with a cryoprobe at a temperature of -196 degrees C. The survival time ranged between 12 h and 21 days. One h before killing, tritiated thymidine was injected intraperitoneally. Stripping film autoradiograms of the brain sections were made in the usual manner. A typical cryonecrosis develops 12 h after local freezing surrounded by an edematous tissue layer with activated mesenchymal and neurologlial cells. After 10 days a pseudocyst develops surrounded by highly cellular glial tissue. The pseudocyst is still recognizable 3 weeks later but without any remarkable cellular reaction. Autoradiographically the labeling indices of the fibroblasts, leptomeningeal,and endothelial cells in the periphery of the necrosis and the labeling indices of neuroglial, perivascular connective tissue, and microglial cells in the perinecrotic zone increase after 12 h and have their maximum between the 2nd and 3rd postoperative day. In the nonfrozen contralateral cerebral hemispheres, the labeling indices of neuroglial and mesenchymal cells show small peaks in the first 3 postoperative days,also. This can be explained by accompanying edema. There are no remarkable differences between frozen and nonfrozen parts of the brain 3 weeks after local freezing. The results underline the rapid repair of cryonecrosis.

Animals↗