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S M Bakhramov

Publications and source records attributed to S M Bakhramov.

12 recordsLinked to original sources

[Program for reducing infant mortality in the Uzbek SSR].

A causal analysis of neonatal mortality has been done in the Uzbek SSR in terms of the socioeconomic life, sociohygienic culture, state of the biosphere, demographic characteristics, and medical care of the population. A complex scientific-practical programme of improvement of mother and child care, that has been introduced in the republic, allowed for stabilization of maternal mortality rates, reduction in preterm births, and for the general decrease in neonatal mortality rates.

Humans↗

[Population genetics study of hemoglobinopathies in Uzbekistan. II. Population dynamics of hemoglobinopathies].

It was shown that on comparing variability of selective neutral genetic marker systems with that of the beta-thalassemia system for the populations of different hierarchical level, the relative importance of selection and genetic drift could be evaluated. The genetic differentiation of the beta-thalassemia gene frequencies in elementary populations (villages) could be solely explained by genetic drift. On the other hand, the differentiation of district populations (the sizes of the populations being 10(6] for beta-thalassemia gene frequencies could be explained by selection forces. This is supported by the fact that the genetic distances and FST values are only significant for the beta-thalassemia gene and not for the neutral genetic systems, when the district populations are compared.

Genetic Markers↗

[Frequencies of ABO system blood groups and haptoglobins in Uzbekistan. The problems of sampling studies].

The results of the analysis of the distribution of blood group gene frequencies of ABO and haptoglobins (Hp) systems for four regions of Uzbek SSR are presented. Three sources were used for sampling: 1) subtotal population samples in 6 villages (the total of 1839 specimens were assayed for ABO and 1729 for Hp); 2) unselected sampling among school children from some districts (2662 specimens assayed for ABO and 3582 for Hp systems); 3) sampling in 18 955 random philanthropic donors from various districts of Uzbekistan. Estimations of blood group gene frequencies were obtained: for the first source--IO = 0.5291; IA = 0.2529; IB = 0.2180; HpI = 0.2510. For the second source--IO = 0.5549; IA = 0.2434; IB = 0.2017; HpI = 0.2783. For the third source--IO = 0.5614; IA = 0.2404; IB = 0.1982. It was established that the frequencies of O(1) blood group of ABO system were permanently increasing, from the values obtained in subtotally investigated villages (kishlaks) toward sampling among school children and reaching the highest value obtained from the sampling in random philanthropic donors (0.5291 leads to 0.5549 leads to 0.5614). The differences are statistically significant. There is strong evidence that it is important for the sampling to be corresponding to the sex-age distribution of populations studied.

ABO Blood-Group System↗