PubMed Health⌕ Search

Biomedical subjects

S M Belotsky

Publications and source records attributed to S M Belotsky.

3 recordsLinked to original sources

Wound tissue respiratory burst and local microbial inflammation.

Local and systemic chemiluminescent (CL) response was measured in 32 patients with wound infection and in 27 patients with crush syndrome complicated by severe wound infection. The level of wound CL depends upon the local microbial concentration and the dynamics of wound healing. CL response of neutrophils in circulation was higher in higher local CL response, but extremely high wound microbial concentration (greater than 10(8) CFU/g) suppressed both local and systemic responses. No metabolic reserve was observed in wound tissue. Wound healing was characterized by changes in the mode of local CL response: from a prevalence of luminol-dependent (neutrophilic) CL to a prevalence of lucigenin-independent (macrophagal) CL.

Bacterial Infections↗

Homologous blood syndrome in dogs. Effect of erythrocyte and platelet antibodies.

Isovolemic perfusion of 50% of the recipient circulating blood volume was carried out in intact mongrel dogs using whole donor blood as well as plasma or platelet suspensions in saline. Perfusion against the background of circulating red blood cells (RBC) or platelets antibodies in the donor or in the recipient was followed by severe and sometimes fatal homologous blood syndrome in a majority of the dogs. Weak and short-term reactions were seen in a few dogs if red blood cells and platelet antibodies were absent.

Animals↗