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S M Butkhuzi

Publications and source records attributed to S M Butkhuzi.

8 recordsLinked to original sources
PubMed1990

[The effect of stimulation of the central gray substance on the neuronal activity of the trigeminal nerve nucleus].

Stimulation of different central gray matter areas (CGM) has been estimated comparatively for its study on the neuronal activity of the trigeminal nucleus during nociceptive stimulation prior to and after the section of the medial brain stem structures between the CGM caudal part and the dorsal raphe nucleus. The possible role of the opiate and nonopiate systems in the mechanism of inhibition of the nociceptive afferentation has been also considered. Experimental data show that in the regulation of the nociceptive afferentation the CGM is a functionally nonuniform structure: in addition to the pain-suppressing system, there is also the pain-relieving system there: inhibitory influence of different CGM areas is accomplished by both the opiate and nonopiate system; the opiate inhibition is mediated by activation of neurons of the raphe nucleus, while the nonopiate one by recruitment of the lateral pathways or activation of the rostral structures of the brain.

Animals↗
PubMed1989

[Effects of clopheline on impulse activity of neurons in the midbrain and dorsal horn of the spinal cord].

Clophelin (1-5 mg/kg) suppresses spinal dorsal horn neuronal nociceptive responses but does not change their touch stimuli reactions in unanesthetized curarized cats. This effect is steady to naloxone (1 mg/kg), yohimbine (5 mg/kg) and removal by prazosin (1 mg/kg). Clophelin depresses nociceptive responses of the central gray matter neurones which generalized pain impulses in the supraspinal structures.

Animals↗
PubMed1977

Spinal trigeminal tractotomy and nociceptive reactions evoked by tooth pulp stimulation in the cat.

The effect of transection of the descending root of the spinal trigeminal tract on nociceptive and aversive reactions evoked by stimulation of the tooth pulp nerve was studied in cats. The transection was performed 1-1.5 mm caudally to the obex. 1. The nociceptive reaction, characterized by wide opening of the jaw, dorsiflexion and rotation of the head and by signs of affective behaviour, remained unchanged after transection of the descending root of the trigeminal nerve (n = 6). 2. The instrumental escape reaction was elaborated in three cats before transection of the descending root of the trigeminal nerve and in three cats after transection. The escape reaction was retained after transection of the descending root and the speed of learning to escape the tooth pulp stimulation did not significantly differ in these two groups of animals. 3. It is to be concluded that the transection of the descending root of the spinal trigeminal tract in the cat does not result in dental analgesia.

Animals↗