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S M Girgis

Publications and source records attributed to S M Girgis.

At least 19 recordsLinked to original sources
PubMed1985

Diagnostic value of vaso-seminal-vesiculography.

The site of obstruction was evaluated by seminal vesiculography in 24 cases of azoospermia with normal testicular biopsies. In 21 cases, obstruction was located at the level of the tail of the epididymis; in 2 cases ejaculatory duct was obstructed; and in 1 case the injected dye was arrested at the level of internal inguinal ring, at the site of previous hernia operation. Vesiculogram in 24 obstructed cases and 4 cases of chronic seminal vesiculities without obstruction showed one normal picture, four with catarrhal inflammation, and the rest with chronic interstitial vesiculities. Radiological study of a patient complaining of aspermia showed multiple congenital anomalies. The high incidence of chronic vesiculities and postinflammatory obstruction is attributed to underlying bilharziasis.

Adult↗
PubMed1985

Zona-free hamster egg-sperm penetration assay: I. Testing of human semen fertilizability.

The zona-free hamster egg penetration test was performed on semen samples from 21 fertile donors, 57 infertile patients with normal semen parameters, and 63 infertile patients with subnormal spermiogram, as well as on 19 frozen semen samples. In the donor group 100% of the samples gave a positive range of penetration (PRP) of 20-96% with a mean penetration rate (MPR) of 53%, while 84% of the frozen samples showed a PRP of 18-44% and an MPR of 31%. Although 74% of the samples from infertile patients with normal spermiograms gave a PRP of 11-92% and an MPR of 34%, only 46% of the semen samples from the infertile patients with subnormal spermiogram showed a PRP of 21-100% but an MRP of 43%.

Animals↗
PubMed1985

Zona-free hamster egg-sperm penetration assay: II. Correlative study with routine semen analysis.

This work studied the effect of variations in the different parameters of routine semen analysis on the penetration rate of the spermatozoa into the zona-free hamster eggs, using semen samples from 21 fertile donors, 57 infertile patients with normal spermiograms, 63 infertile patients with subnormal spermiograms, and 19 frozen semen samples. The results of the hamster test do not correlate with the percentage of motile spermatozoa, the percentage of live spermatozoa, or the percentage of spermatozoa with normal morphology in the semen samples. A positive correlation was found between the results of the hamster test and three other parameters of the semen analysis: the sperm concentration, the progressive type of motility, and a pH range of 7.2-7.7, but these positive correlations were statistically insignificant.

Animals↗
PubMed1985

Value of intraprostatic injection of zinc and vitamin C and of ultrasound application in infertile men with chronic prostatitis.

Seventy infertile men with chronic prostatitis were treated by prostatic massage and wide-spectrum chemotherapy as basic treatment to which intraprostatic injection of zinc or vitamin C with or without ultrasound application was added as a new line of treatment. Comparison showed no significant improvement of the additive treatment over the conventional treatment used alone. Pus cells in the expressed prostatic smear diminished significantly after treatment, which was associated with significant increase of percentage of motile spermatozoa and significant decrease of abnormal forms. Bacterial flora was studied in comparison with findings in 20 cases of infertile males without prostatitis; staphylococci predominated in both patient and control groups.

Adult↗
PubMed1984

Testicular biopsy in azoospermia and severe oligozoospermia.

The continued experience of testicular biopsy application in 861 cases of azoospermia and 152 cases of severe oligospermia is reported adding to the previously published cases of 1075 patients with azoospermia. The most common finding in the whole series was that of normal testis denoting obstruction (48%), while among cases of functional azoospermia, Sertoli cell only and spermatogenic arrest were the most frequent (66%).

Adult↗
PubMed1983

Treatment of asthenozoospermia by intratesticular testosterone therapy.

A single intratesticular injection of 0.5 cc of 50 mg/ml of an aqueous testosterone suspension was administered to 14 patients with asthenozoospermia. In 7 cases, injection was combined with ultrasound of 0.5 w/cm2 for 2 min weekly for 4 weeks. In another 4 cases, only ultrasound was applied. Intratesticular injection with or without ultrasound caused a significant increase of motility percentage. Sperm density improved in cases that were associated with oligozoospermia (less than 20 million/ml). Ultrasound therapy (0.5 w/cm2 for 2 min) used alone had no effect on semen parameters. Associated hormonal changes in blood plasma were evaluated.

Adult↗
PubMed1983

FSH, LH, E2, progesterone, and testosterone in peripheral blood, spermatic vein, and semen of subfertile men with varicocele.

Peripheral blood (PB), spermatic vein (Sp. V.), and semen samples were collected from 31 subfertile men with varicocele. Levels of FSH, LH, estradiol, progesterone, and testosterone were determined in the three biological fluid compartments using RIA. Remarkable increases in both testosterone and estradiol in the spermatic vein samples, as compared to either peripheral blood or semen, were evident. Correlation coefficient indicated significant positive correlation between PB FSH and each of PB LH, Sp. V. FSH, and Sp. V. LH. Significant positive correlation existed between PB LH and each of Sp. V. FSH, LH, and testosterone. Significant positive correlations were found between PB testosterone and each of Sp. V. testosterone and semen testosterone, as well as between PB estradiol and each of Sp. V. FSH and progesterone. Significant positive correlations between Sp. V. FSH and Sp. V. testicular progesterone was significantly correlated with seminal estradiol.

Adult↗
PubMed1982

Sperm antibodies in serum and semen in men with bilateral congenital absence of the vas deferens.

Sperm antibodies were evaluated in serum and semen of 14 cases with bilateral congenital absence of the vas deferens, by agglutination and complement dependent tests. The level of the various immunoglobulin fractions were determined by the single radial immuno diffusion method. Sperm agglutinins were present in serum in 71% of cases and in 29% in semen. Immunoglobin (Ig) M was not detected in semen of both patient and control groups, while IgG and IgA were absent in the semen of patients.

Adult↗
PubMed1981

Unconventional protein sources: apricot seed kernels.

Hamawy apricot seed kernels (sweet), Amar apricot seed kernels (bitter) and treated Amar apricot kernels (bitterness removed) were evaluated biochemically. All kernels were found to be high in fat (42.2--50.91%), protein (23.74--25.70%) and fiber (15.08--18.02%). Phosphorus, calcium, and iron were determined in all experimental samples. The three different apricot seed kernels were used for extensive study including the qualitative determination of the amino acid constituents by acid hydrolysis, quantitative determination of some amino acids, and biological evaluation of the kernel proteins in order to use them as new protein sources. Weanling albino rats failed to grow on diets containing the Amar apricot seed kernels due to low food consumption because of its bitterness. There was no loss in weight in that case. The Protein Efficiency Ratio data and blood analysis results showed the Hamawy apricot seed kernels to be higher in biological value than treated apricot seed kernels. The Net Protein Ratio data which accounts for both weight, maintenance and growth showed the treated apricot seed kernels to be higher in biological value than both Hamawy and Amar kernels. The Net Protein Ratio for the last two kernels were nearly equal.

Fruit↗
PubMed1981

Unconventional protein sources: "date seeds".

Different varieties of Egyptian date seed were evaluated biochemically. The protein content of which was in the range of 7.13-10.36%, while the fat content was from 6.32-9.28%. Phosphorus, calcium and iron were determined in all experimental samples. One variety of date seed (Samany) were used for extensive determination of the amino acids constituents by acid hydrolysis, quantitative determination of some amino acids, and evaluation of their biological value on attempt to use the seeds as new protein sources. Weanling albino rats fed on a diet of protein level 5% lost weight, but no toxic signs were observed. Analysis of blood serum of rats, for total proteins, albumin globulin ratio and free nonessential/essential amino acid protein, showed the date seed protein to be of low biological value.

Animals↗
PubMed1981

Endocrine profile of semen in subfertile males with varicocele.

The semen levels of FSH, LH, estradiol, progesterone, and testosterone were estimated in normal fertile males and in patients with oligozoospermia and varicocele. The only significant difference between the mean values of the two groups was noted for semen LH. Patients with oligozoospermia and varicocele had lower level than the normal fertile males. As a function of prostatic infection, no significant difference was obtained.

Aged↗
PubMed1981

Clinical and hormonal studies of subfertile males with varicocele.

To evaluate the hormonal factor in subfertile males with varicocele, FSH, LH, estradiol (E2), and testosterone (T) were assayed both from cubital and spermatic veins. The hormonal profile of patients showed no significant differences from the normal control group. Blood hormonal levels of E2 and T in the testicular veins were much higher than those in the cubital veins while FSH and LH levels showed no significant difference. FSH, LH, and testosterone blood levels in cubital and spermatic veins were statistically correlated. A preoperative hormonal study would be helpful in excluding cases in which varicocele is not the underlying cause of infertility.

Adult↗
PubMed1980

Effect of acute and chronic simulated high altitude on male reproduction and testosterone level.

Forty, sexually mature, male rats were divided into two control and two treated groups. One of the treated groups was exposed five times to 6000 m of high altitude (acute exposure), and the other treated group was exposed 70 times (chronic exposure). Acute exposure had no pathological effect on the male reproductive tract or blood testosterone level; however, in animals that received chronic exposure, there was significant reduction in plasma testosterone level, 80% of spermatogenic tissue was highly vacuolated, nuclei of the interstitial tissue revealed pyknosis, and dilation of the blood vessels was noted throughout the testis.

Altitude↗
PubMed1980

Bilharziasis and azoospermia.

Two patients in their twenties were investigated for a complaint of primary sterility. Semen analysis, showed azoospermia and testicular biopsy showed inhibited spermatogenesis in association with bilharzia ova in the interstitium in both cases. No similar cases were reported previously in the literature.

Adult↗
PubMed1979

Serum sperm antibodies in cases of azoospermia: comparative diagnostic value of separate and combined, agglutination, immoblization and cytotoxic serological tests.

To study the diagnostic value of various serological tests in the detection of serum sperm antibodies a group of 50 patients with azoospermia was studied. Cases were divided by testicular biopsy into: 32 obstructive and 16 non obstructive cases. Tests applied included a microagglutination and a macroagglutination test as well as 2 complement dependent tests; a sperm cytotoxic and a sperm immobilization tests. Applied separately the macroagglutination was the most sensitive test but used together, more cases were detected. Because of this and the different value and significance of each test, it is advisable to use more than one test in the investigations of cases of male infertility.

Adult↗
PubMed1979

Endocrine studies of azoospermia. II. Serum steroid levels in obstructive azoospermia.

Serum estrone, estradiol, estriol, progesterone, 17 alpha-hydroxyprogesterone, and testosterone were determined in the sera of 25 normal males and 25 patients with obstructive azoospermia. An increase in testosterone and estriol levels, and a decrease in other hormones were demonstrated in patients with obstructive azoospermia. These long-term effects of obstruction of the vas apparently also occur in comparable situations, for example, after vasectomy.

Adult↗
PubMed1979

Local male hormonal therapy in male infertility: a preliminary report.

The therapeutic effect of local infiltration of the testis by testosterone crystalline suspension was studied in 18 cases of severe oligozoospermia. Evaluation was done by semen analysis follow-up, and results were correlated with preoperative testicular biopsies. About 40% of the cases showed improvement of sperm count and/or motility. Testicular biopsies of responding cases showed mild inhibitory changes, such as sloughing or partial spermatogenic arrest at late stages, while cases with tubular hyalinization or spermatogenic arrest at the stage of spermatogonia showed no response. The method proved to be simple, safe, and promising.

Adult↗