[Comparison of water, electrolyte and nitrogen balance in the postoperative period after epidural or general anesthesia. A randomized study patients undergoing hysterectomy].
Explore the source record for details and available documents.
Adult↗
Biomedical subjects
S M Gregoretti
Publications and source records attributed to S M Gregoretti.
Influence of oral atropine or hyoscine on the absorption of oral diazepam.
The influence of oral atropine or hyoscine on the absorption of oral diazepam administered at the same time was studied in eight volunteers using a three-way crossover randomized double-blind design. No difference was found in the timing of sedation or in the degree of sedation after diazepam alone or in combination with the anticholinergics. Diazepam serum concentrations were not significantly different after the three regimens. It is concluded that the anticholinergics can be given with diazepam for oral premedication without interfering with diazepam absorption.
Administration, Oral↗
Heart rate and blood pressure changes after ORG NC45 (vecuronium) and pancuronium during halothane and enflurane anesthesia.
Explore the source record for details and available documents.
Adolescent↗
Interactions between morphine and doxapram in the rabbit and mouse.
Certain actions of doxapram, administered alone and in combination with morphine, have been examined in the rabbit and the mouse. Single doses of doxapram were capable of stimulating respiration in both species. There was an increase in tidal volume in the rabbit and an increase in respiratory rate in the mouse. In both species the duration of action of single doses of doxapram was less than 15 min. In morphine-treated rabbits and mice single doses of doxapram affected neither the time course nor the intensity of the respiratory depression. In the rabbit repeated doses of doxapram did not produce tachyphylaxis with respect to the effect on tidal and minute volumes, and effectively reversed the respiratory depressant actions of morphine. The usefulness of this action must be balanced against the enhanced toxicity of doxapram observed in morphine-treated mice.
Animals↗