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Biomedical subjects

S M Hutchison

Publications and source records attributed to S M Hutchison.

14 recordsLinked to original sources
PubMed1997

Uterine arterial vasoconstrictions mediated by ovarian nerves in virgin and postpartum rats.

In most mammals, including humans, pregnancy results in the loss of most uterine vasomotor fibers. These experiments determined whether, despite this denervation, sympathetic nerves mediated uterine vasoconstrictions in the rat 24 h after delivery. Both virgin and uniparous postpartum rats were anesthetized with urethan. Femoral vessels were cannulated for measurement of arterial pressure and intravenous administration of fluids and drugs. Blood flow was measured in a uterine artery after ligation of all anastomotic ovarian vessels. Electrical stimulation of ovarian nerve efferents elicited frequency-dependent uterine vasoconstrictions in both virgin and postpartum rats. Vasoconstrictions in postpartum rats were not significantly different from those observed in virgins. In both virgin and postpartum rats, neurogenic vasoconstrictions were reduced by combined alpha 1- and alpha 2-adrenergic blockade. We conclude that the uterine branches of the ovarian nerve mediate adrenergic uterine vasoconstrictions. In the largely denervated uterus of the postpartum rat, these vasoconstrictions may be mediated by surviving innervation of the uterine artery and its major branches. Sympathetic vasoconstriction acting at these sites would constitute an effective defense against postpartum hemorrhage.

Adrenergic Antagonists↗
PubMed1995

Evaluation of bereavement anniversary cards.

The anniversary of a death is perceived as a difficult time by the majority of closely bereaved relatives and friends. Bereavement anniversary cards are supportive and useful in the context of wider follow-up. This study identified no strong predictors to indicate those for whom such a card would be inappropriate. Several recipients thought that the card solicited financial support for the hospice.

Adult↗
PubMed1987

Case note chaos: prevention is better than cure.

The long term storage of hospital clinical records is becoming a big problem. A great reduction in the bulk of case notes can be achieved by compartmentalizing unstructured case notes. Such a system has many advantages for medical staff, and its widespread use would do much to alleviate storage problems in future years.

Forms and Records Control↗
PubMed1987

Epistaxis as a cause of hematemesis and melena.

Epistaxis was diagnosed in 10 patients with apparent upper gastrointestinal bleeding, comprising a 0.55% incidence of hematemesis and melena in the population studied. A sufficient amount of blood can be swallowed during epistaxis to cause hematemesis and melena. Recent facial trauma or epistaxis, absence of a history of chronic dyspepsia, and impairment of blood coagulation emerge as strong indicators of the diagnosis and should lead to a careful examination of the nose and nasopharynx for the source of bleeding.

Adult↗