PubMed Health⌕ Search

Biomedical subjects

S M Kaplan

Publications and source records attributed to S M Kaplan.

At least 19 recordsLinked to original sources
PubMed1992

The occupational hazards of jury duty.

Jurors on criminal trials carry a considerable burden of responsibility. They determine the defendant's fate. Additionally, during trials they can be exposed to stressful, frightening, and sordid aspects of life. The stressfulness varies depending upon the nature of the trial, its length, the nature of the testimony and evidence, the jurors' interpersonal relationships, the difficulty establishing guilt or innocence, the public's attitude, etc. These experiences can create psychological and/or physical discomfort that can be transient and mildly or moderately intense, or more serious and constitute illness. The authors have studied juries of four criminal trials--two murder cases, one child abuse case, and one obscenity case. Forty jurors were interviewed. Twenty-seven had one or more discomforting physical and/or physiological symptoms. These involved gastrointestinal distress (10 jurors); generalized nervousness (4 jurors); heart palpitation (6 jurors); headaches (4 jurors); sexual inhibitions (4 jurors); depression (4 jurors); anorexia (4 jurors); faintness (2 jurors); and numbness, lump in throat, chest pain, hives, and flu (1 juror each). Seven of the jurors became clearly ill. Illnesses included: peptic ulcer reactivation and hives, phobic reaction, anxiety state and increased alcohol use, hypertensive episode and visual scotomata, sexual inhibition, chills, fever, and depression, and post-traumatic stress disorder.

Adult↗
PubMed1991

An evaluation of the possible protective effects of neonatal striatal transplants against kainic acid-induced lesions.

The present study examined the recent report that transplantation of neonatal striatal tissue into kainic acid (KA) lesioned striatum protected the contralateral striatum from a subsequent KA lesion. We did not find a significant difference in the survival rate of animals that received neonatal striatal transplants into a KA lesioned striatum followed by a subsequent lesion of the contralateral striatum compared to those animals that received bilateral KA-induced striatal lesions alone. The tissue transplants did not protect against the degeneration of striatal neurons induced by KA. Indeed, the survival rate was very low (25%) in the transplant groups. A second experiment was also performed to examine whether a neonatal striatal transplant might reduce the severe syndrome of aphagia and adipsia associated with KA lesions of the striatum. Animals that received the neonatal striatal transplants showed increased aphagia and adipsia compared to animals only receiving the KA lesion. Again, the transplant group had a very low survival rate (10%). The present study was unable to confirm that neonatal striatal transplants protect against KA lesions either by themselves or in conjunction with a recent KA lesion.

Animals↗
PubMed1991

Iliopectineal bursitis: an unusual cause of iliofemoral vein compression.

The iliopectineal bursa is the largest bursa in the region of the hip joint. Enlargement of the bursa occurs in several conditions and may be manifested by groin pain, a pelvic or inguinal mass, or lower extremity edema due to compression of the external iliac or common femoral vein. A case of lower extremity edema secondary to external iliac/common femoral vein compression caused by an enlarged iliopectineal bursa is presented. The pathophysiology, methods of diagnosis, and forms of therapy are discussed.

Arterial Occlusive Diseases↗
PubMed1985

Exercise training during long-term beta-blockade treatment in healthy subjects.

Although it is well accepted that treatment with beta-blocking drugs impairs endurance exercise capacity acutely, whether a trained state can be achieved while receiving long-term beta-blocker therapy is controversial. The apparent attenuation of training reported in some studies has given rise to the theory that adrenergic stimulation represents a unifying mechanism by which endurance training effects are produced. This theory is supported by studies of long-term beta-agonist infusions that show apparent training responses. To assess the role of beta-adrenergic stimulation produced by exercise in the development of cardiovascular training effects, 39 healthy men were assigned in a random, double-blind fashion to receive oral propranolol, atenolol or matched placebo. Drug doses were titrated individually to minimize the heart rate response to submaximal exercise (dose ranges: atenolol, 50 to 200 mg/day; propranolol, 160 to 320 mg/day). After beginning chronic drug administration, all subjects participated in an intense, supervised 6-week exercise training program (5 days/week, 45 min/day, at least 75% peak heart rate). Adherence to training was monitored by daily supervision; compliance to the medication regimen was assessed by weekly pill counts, medication diaries and plasma drug assay. Maximal exercise testing was performed before and after training. Peak oxygen consumption increased significantly with training in all 3 groups, whether comparisons were made in the presence or absence of medication. The magnitude of change in oxygen consumption did not differ between groups (F = 0.12, p greater than 0.88). Similarly, peak work rate and duration of work increased in all 3 groups.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1985

The new health care: the Blue Cross and Blue Shield organization's response to change.

The swift changes in the delivery and financing of health care have created something which the Blue Cross and Blue Shield organization has called "The New Health Care". Encompassing health maintenance organizations, preferred provider organizations, and managed care options, it is designed to help control health care costs by providing choice and flexibility for consumers and providers of care.

Blue Cross Blue Shield Insurance Plans↗
PubMed1977

Hepatic regeneration and erythropoietin production in the rat.

The regenerating liver produces erythropoietin in response to hypoxia. The amounts of erythropoietin produced in animals subjected to hepatectomy are significantly higher than those observed in sham-operated animals. Hepatic erythropoietin production appears to be dependent upon the stage of regeneration with the highest levels being produced during the period of greatest proliferation and increase in liver mass.

Animals↗
PubMed1975

Loss with age in the capacity for erythrogenin production by extrarenal tissues in rats.

Erythrogenin levels in liver and spleen were compared in young and adult anephric rats exposed to 6h of hypoxia. Hepatic and splenic erythrogenin levels in young nephrectomized rats were significantly higher than those in anephric adults. This lowered ability of the adult rat to elaborate extrarenal erythrogenin may be related to a decrease in selective enzyme production which accompanies the aging process.

Aging↗