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Biomedical subjects

S M Lindenauer

Publications and source records attributed to S M Lindenauer.

At least 73 records · Page 4Linked to original sources
PubMed1976

Major arterial hemorrhage: a complication of pancreatic pseudocysts and chronic pancreatitis.

Twelve patients (11 men, one woman), aged 18 to 68 years, had major arterial hemorrhage as a direct complication of pancreatic pseudocysts and chronic pancreatitis. Chronic alcoholism (11 patients) and blunt abdominal trauma (one patient) were the basis for pancreatic disease. Spontaneous hemorrhage occurred in eight patients. Bleeding occurred into the gastrointestinal tract (eight patients), into the peritoneal cavity (four patients), and was intracystic (one patient). Splenic, pancreaticoduodenal, gastroduodenal, and gastroepiploic arteries were sources of hemorrhage. Operative procedures included local control of bleeding (six patients), distal pancreatectomy (three patients), and pancreaticoduodenectomy (one patient). Four patients died of hemorrhagic complications of pancreatic disease, including one not subjected to operation. Extirpation of diseased pancreatic tissue may lessen the morbidity and mortality attributed to this complication of pancreatitis.

Adolescent↗
PubMed1976

Pelvic exenterative therapy for gynecologic malignancy: an analysis of 70 cases.

During the 10-year period from June 1, 1965 to June 1, 1975 70 patients with gynecologic malignancy were treated with some type of pelvic exenteration at the University of Michigan Medical Center. Total pelvic exenteration was performed in over 75% of the cases. The most recent figures suggest a 3-year and 5-year survival rate of over 60%. The surgical mortality is 1.4%: the hospital mortality is 1.4%. Those patients with squamous cell disease, such as recurrent carcinoma of the cervix, vagina or vulva, have a better prognosis than do those patients with gland cell disease. Regional lymph node involvement gives a bad prognosis. Advances in therapeutic techniques during this 10-year period, including: 1) use of prophylactic antibiotics: 2) transverse abdominal incision; 3) so-called "ski-position" on the operating table; 4) prophylactic compartmentalization of the inferior vena cava; 5) uretero-sigmoid conduit for urinary diversion; 6) peritoneal graft as a "lid" over the pelvic vault' and 7) split-thickness skin graft vaginoplasty as part of the rehabilitation program, are discussed.

Female↗
PubMed1976

Long-term patency of vein grafts preserved in liquid nitrogen in dimethyl sulfoxide.

Autogenous canine jugular veins were stored in 15% dimethyl sulfoxide (DMSO) in liquid nitrogen vapor for one to 28 days and then implanted in the carotid artery as autografts. The patency rate at one year was 62.5-87.5%. The patency rate of fresh jugular vein autografts placed in the carotid artery for one year was 75%. Similar autografts stored in liquid nitrogen vapor for one to 28 days without the cryopreservative DMSO exhibited a zero to 12.5% patency rate at one year. Scanning electron microscope studies revealed preservation of theendothelium in DMSO protected veins and a damaged or sloughed endothelium in veins frozen without DMSO cryopreservation.

Animals↗
PubMed1976

Focal infection of aortofemoral prostheses.

A canine model of unilateral aortofemoral bypass was utilized to study periprosthetic infections in woven, knitted, and velour Dacron vascular prostheses. These studies suggest that physical configuration, porosity, and time of inoculation all are important variables when managing an infected prosthesis, although size of inoculum seems less important.

Abscess↗
PubMed1976

The use of velour as a vascular prosthesis.

Knitted Dacron cloth fabricated into tubes has gained widespread acceptance as an arterial prosthesis. Continued research and development in the field of vascular prostheses is required because existing materials are not ideal. This paper relates general developments in vascular prosthesis research and focuses on specific results with Dacron velour materials. The nature of the velour surface offers several advantages that are important in designing a more satisfactory prosthesis.

Animals↗
PubMed1976

Perforation of the normal colon during barium contrast examination.

Two cases of perforation of the normal colon during barium contrast examination are reported. Overdistention of the colon with air and barium contrast examination are reported. Overdistention of the colon with air and barium should be avoided in a patient with a competent ileocecal value. While rare, this complication can be life-threatening.

Aged↗
PubMed1975

Management of the recurrent ulcer.

One hundred seventeen patients with recurrent ulcer were treated at the University of Michigan Medical Center. The most satisfactory results were obtained when vagotomy was employed in the surgical therapy. Seventy-one of 91 patients treated by operation had a satisfactory result. In nine patients a second operation was required, and three patients underwent a third operative procedure. Twenty-one additional patients were satisfactorily treated medically so that, overall, 92 of 117 patients (79%) had a good result. Twelve patients had residual symptoms and 13 were lost to follow-up. There were no deaths attributable to recurrent ulcer in the entire series.

Adult↗
PubMed1975

133Xe muscle clearance: a screening test for arterial occlusive disease.

133Xe muscle clearance following ischemic exercise provides a simple, well-tolerated screening procedure for evaluating patients suspected of having arterial occlusive disease in the lower extremeties and may be useful in the follow-up of patients who have undergone corrective arterial surgery. It can be performed in nuclear medicine units capable of doing renography, and the authors feel it should be used prior to undertaking more invasive procedures such as arteriography. Methods and results of tests involding 92 legs in men are described.

Adult↗