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Biomedical subjects

S M Ramadan

Publications and source records attributed to S M Ramadan.

5 recordsLinked to original sources
PubMed1992

Adenohypophyseal activity in relation to suprarenal function in tuberculosis.

This work was carried out on 150 subjects. They were classified into four groups: group I: Bronchogenic pulmonary T. B. (n = 96); group II: Haematogenous T. B. (n = 15); group III: Healed T. B. (n = 16), group IV: Healthy control (n = 23). Insulin tolerance test was done for each subject to assess the hypothalamo-hypophyseal axis. Glucose, ACTH, cortisol, GH, and PRL levels were estimated during fasting and over three hours after insulin administration. In group I and II the patients exhibited higher fasting levels of anti-insulin hormones and they respond greater than normals to insulin-induced hypoglycaemia. This might indicate early affection of the pituitary gland by TB infection, yet insulin-induced hypoglycaemia assured efficient function of the gland. In healed TB patients, no significant changes were obtained in the different hormonal behaviour, whether in the fasting state or after stimulation. This might be explained by improvement of the health condition of the patients, and relief of the stress induced by TB infection.

Adrenocorticotropic Hormone↗
PubMed1992

Plasma catecholamines in pulmonary tuberculosis.

Fifty pulmonary tuberculous patients (minimal; moderate and far-advanced), 18 TB-healed persons and 15 healthy control subjects were examined for plasma levels of adrenaline (AD), noradrenaline (NA), dopamine (DA), ACTH and cortisol. The estimated hormones were found to be increased significantly with the severity of the disease suggesting that the stress of infection plays a role in induction of enzymes responsible for catecholamines synthesis with subsequent stimulation of ACTH and cortisol secretion. Noradrenaline appeared the most effective in this respect.

Adrenocorticotropic Hormone↗
PubMed1981

Repetitive activity of a molluscan neurone driven by maintained currents: a supercritical bifurcation.

The amplitude and rate of transient and maintained responses of an identified giant neurone of the pond-snail, Lymnaea stagnalis, to a maintained injected current were investigated. The responses of the isopotential soma to a maintained current density of less than 10 microamperemeter cm -2 includes repetitive discharges of action potentials, sawtooth oscillations and amplitude-modulated oscillations. The frequency of the maintained response increases as the injected current increases, while the amplitude decreases until the maintained response is a stable steady state at a membrane potential of about -20 mV. This bifurcation from small amplitude periodic solutions to a depolarized stable steady state has the characteristics of a supercritical Hopf bifurcation.

Action Potentials↗