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Biomedical subjects

S M Sajjad

Publications and source records attributed to S M Sajjad.

13 recordsLinked to original sources

Primary hepatic leiomyosarcoma.

We describe a case of primary hepatic leiomyosarcoma and review the previous reports on this entity. We stress the histologic differentiation of this tumor from similar neoplasms and point out the need for aggressive resection in operable cases.

Aged↗

Giant cell arteritis of the skin simulating erythema nodosum.

Cutaneous involvement in giant cell arteritis is quite uncommon. A patient is described who presented with pretibial skin lesions clinically indistinguishable from erythema nodosum which, on biopsy, showed subcutaneous pannicular giant cell vasculitis. Cutaneous manifestations of giant cell arteritis are subsequently reviewed.

Diagnosis, Differential↗

A trichrome stain for intrahepatic localization of hepatitis B surface antigen.

A modified trichrome stain was used to detect hepatitis B surface antigen (HBsAg) in liver tissue obtained at the time of autopsy. The infected hepatocytes exhibited a selective green metachromasia of their cytoplasma, corresponding with the intracytoplasmic presence of HBsAg as confirmed by immunofluorescent and immunoperoxidase techniques. The trichrome technique for staining HBsAg is easy to perform, reliable, and can be used for routine histologic screening of HBsAg in liver disease.

Azo Compounds↗

Lymph node involvement by histiocytosis X.

Lymph node involvement by histiocytosis X is usually secondary to nearby bone or skin lesions. A patient with histiocytosis X confined to lymph nodes is rarely seen; however, we studied two such persons. In each, a lymph node biopsy was performed because the clinical aspects caused us to suspect neoplastic disease.

Adult↗

Fibrous histiocytoma of lung--a clinicopathological study of two cases.

Two cases of fibrohistiocytic tumours of the lung are presented and histogenesis of this group of this group of tumours is discussed. An essentially biphasic pattern of histiocytes and fibroblasts, and the presence of myofibroblasts and undifferentiated mesenchymal cells is similar to the fibro histiocytic neoplasms in other locations.

Aged↗

Oncocytic carcinoid tumor of the lung.

A case of bronchial carcinoid tumor is reported in which a marked degree of transformation to mitochondrion-rich cells (oncocytes) was present. Ultrastructural observations demonstrated a transition between the two cell types, and revealed an alteration in mitochondria suggestive of a degenerative change in these organelles.

Adenocarcinoma, Bronchiolo-Alveolar↗

Hyaline inclusions in a synovial sarcoma following intra-arterial chemotherapy.

Hyaline inclusions were noted in cells of a typical synovial sarcoma following intra-arterial chemotherapy. Ultrastructural study revealed that the inclusions were cytoplasmic aggregates of intermediate filaments. Since the inclusions were not present in the tumor prior to treatment, it is suggested that they may have formed as a result of the infusion and that their presence may be an indicator of chemotherapeutic effect.

Cytoskeleton↗