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Biomedical subjects

S M Schleicher

Publications and source records attributed to S M Schleicher.

16 recordsLinked to original sources

Response of hand dermatitis to a new skin barrier-protectant cream.

Twenty-five patients with hand dermatitis participated in a pilot study utilizing a new skin barrier cream containing white petrolatum. Each patient received treatment with SBR-Lipocream, which was applied three to four times daily for a period ranging from one to four weeks. All patients completed pre- and postsurvey questionnaires and were evaluated by a staff physician prior to, and upon completion of, the study. All patients completed the evaluation. Results of the survey indicated a general dissatisfaction with currently utilized moisturizers and a positive response to the skin barrier cream: 96 percent believed that this cream helped their condition. Based on this response, further evaluation of this cream's ability to manage this often-chronic condition and prevent exacerbation and flares appears warranted.

Adolescent

Basal cell carcinoma of the scrotum.

Basal cell carcinoma is the most common human neoplasm, with hundreds of thousands of new cases occurring on an annual basis. Involvement of the scrotum is quite rare, with fewer than twenty-five reported cases. We present a patient with a basal cell carcinoma of the scrotum and review the literature regarding this infrequently documented site.

Aged

Giant cell tumor of tendon sheath.

The giant cell tumor of tendon sheath is a benign histiocytic proliferation of the articular and peritendinous synovial tissue that has only rarely been reported in the dermatologic literature. The lesion manifests as a firm 1 to 3 cm nodule most frequently occurring on the fingers, hands, and wrists, where it is attached to the tendon sheath. Its histopathologic appearance is characterized by the presence of multinucleate giant cells. The author reports a classic example of the giant cell tumor of tendon sheath.

Finger Joint

Congenital nevi.

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Humans

Resolution of disseminated granuloma annulare following isotretinoin therapy.

Disseminated granuloma annulare is often a chronic disorder that may prove refractory to treatment and lead to prolonged cosmetic disfigurement. In a patient with disseminated granuloma annulare that was unresponsive to multiple therapeutic regimens, administration of isotretinoin resulted in rapid clearing of nearly all lesions. To our knowledge this is the first reported case in which this agent was used to treat disseminated granuloma annulare.

Female

Coumarin necrosis.

Necrosis of the skin developed soon after the initiation of coumarin therapy in an elderly woman. Inadvertent rechallenge resulted in similar lesions. Coumarin necrosis is a poorly understood phenomenon unlikely to respond to therapy. Fortunately, its incidence is quite rare, considering the widespread use of this anticoagulant.

Aged