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Biomedical subjects

S M Soliman

Publications and source records attributed to S M Soliman.

9 recordsLinked to original sources
PubMed2002

Urothelial ingrowth over demucosalized gastrocystoplasty: an experimental study.

OBJECTIVE: To evaluate histopathologically the ingrowth of urothelium over a demucosalized gastric flap used for augmentation, as such flaps increase the capacity of the bladder if the urothelium can cover the seromuscular patch. MATERIALS AND METHODS: The study included eight male dogs; the urinary bladder was widely divided at its dome anteroposteriorly to receive a seromuscular gastric flap, sutured to the edges of the urinary bladder. Before and 1 month after surgery the changes in bladder capacity and pressure were recorded, and urothelial ingrowth assessed histopathologically. RESULTS: Two of the eight dogs died; the increase in mean bladder capacity in the remaining dogs was 20% and the decrease in mean intravesical pressure 34%. Gross pathological examination of the urinary bladder showed good 'take' of the gastric flap by the urinary bladder. Histopathologically, there was good healing of the flap, active ingrowth of urothelium, and no mucosal re-growth. CONCLUSION: Bladder augmentation with a demucosalized gastrocystoplasty allows the creation of a large compliant urinary bladder with few complications caused by the incorporation of the enteric or gastric epithelium into the urinary bladder. The stomach has a rich blood supply, allowing the harvesting of a well-vascularized flap, and urothelial ingrowth over this flap in the present study was significant.

Anastomosis, Surgical↗
PubMed2001

Dietary cancer risk from conditional cancerogens (tumor promoters) in produce of livestock fed on species of spurge (Euphorbiaceae). V. Skin irriitant and tumor-promoting diterpene ester toxins of the tigliane and ingenane type in the herbs Euphorbia nubica and Euphorbia helioscopia contaminating fodder of livestock.

Irritant diterpene ester toxins were isolated from Euphorbia nubica and E. helioscopia, which are contaminants of the green fodder of livestock in Egypt. Fractionations of methanol extracts of aerial parts of both plants were monitored by the irritation unit on the mouse ear. Plant extracts were subjected to multiplicative distribution methods, yielding irritant hydrophilic fractions that were further purified by column chromatography. Final purification of the materials was achieved by TLC (silica gel) followed by HPLC, or by TLC alone. In this way, from E. nubica, five Euphorbia factors (Nu1-Nu5) were isolated and characterized as short-chain polyfunctional diterpene esters of tigliane-type parent alcohols. The two weak irritants Nul and Nu3 were triesters of 4-deoxy(4alpha)phorbol. Nu2 was shown to be a triester of the stereoisomeric tigliane-type parent alcohol 4-deoxyphorbol. Weak irritant Nu4 probably is a positional isomer of Nu2. Nu5 was characterized as a short-chain triester of 4,20-dideoxy-5xi-hydroxyphorbol. From E. helioscopia, six short- to medium-chain polyfunctional diterpene esters of the ingenane type, generally containing unsaturated acids were obtained, i.e., four irritant esters of ingenol (Euphorbia factors H1, H2, H5, and H6) and two esters of 20-deoxyingenol (non-irritant Euphorbia substance HS4, and irritant Euphorbia factor H8). All irritant Euphorbia factors of the tigliane and ingenane diterpene ester type described in this investigation are considered to be more or less active tumor promoters, i.e., conditional (non-genotoxic) cancerogens. The Euphorbia factors assayed exhibited moderate (H1) to low (H8) relative tumor-promoting potency in comparison to the ingenane prototype DTE tumor promoter 3-TI.

Alcohols↗
PubMed1998

Lindane degradation and effects on soil microbial activity.

The degradation of U-14C-lindane in two Egyptian soils was determined in a three-month laboratory incubation. Lindane mineralization was slow and limited in both soils. Evolution of 14CO2 increased with time but only reached 3.5 to 5.5% of the initial 14C-concentration within 90 days. At that time both soils contained about 88% of the applied radiocarbon; 33% to 37% of the initial dose was unextractable and assumed bound to the soils. The methanol-extractable 14C primarily contained lindane with traces of minor metabolites. Radiorespirometry was used to evaluate the effect of lindane on soil microbial activity. Low concentrations of the insecticide initially supressed 14CO2 evolution from U-14C-glucose and microbial activity was significantly inhibited by 10 mg lindane/kg soil.

Carbon Dioxide↗
PubMed1994

Triple suspension rectopexy for complete rectal prolapse.

Twenty-eight patients with complete rectal prolapse were treated by a three-level triple suspension abdominal rectopexy with no recurrence and with improvement of rectal function. Rectal suspension was effected by three steel wire slings.

Adolescent↗
PubMed1991

Middle latency auditory evoked potentials in temporal lobe disorders.

Middle latency auditory evoked potentials (MAEP) were recorded in 30 normal subjects and in 19 age-matched patients with temporal lobe lesions. MAEP appeared to be differentially affected by the specific structures involved within the temporal lobe. In the majority of patients with lesions involving the auditory area and/or auditory radiation, Na-Pa amplitude was significantly reduced over the involved hemisphere. No similar reduction in amplitude was noted in subjects with lesions not involving the auditory structures within the temporal lobe. We also observed a shift in a Pa latency over the involved hemisphere in patients with temporal lobe lesions involving the auditory structures. This latency shift was less pronounced than the amplitude reduction. The generators of MAEP in humans are discussed according to these findings and to the available literature. Normal intersubject variability of the conventional amplitude measures, and the occasional myogenic contamination of the response, limits establishing reliable criteria for abnormality that can be applied clinically for the diagnosis of patients with temporal lobe disorders.

Acoustics↗
PubMed1989

Anchorage overlapping repair of incisional hernia.

Fifty-five incisional hernias at different sites were repaired by fashioning strips of the hernial sac with its entire coverings of collagen scar at one side. The strips are reversed through holes made in the superficial overlapping muscular layer and fixed back to the ipsilateral side. There were no major recurrences over a 2-10-year period except for a minor one at the upper end of a vertical repair. The operation was likewise performed with success in 28 patients with para-umbilical hernias. This triple layer anchorage technique is practically and theoretically sound since recurrences due to sliding of layers of simple overlapping repair with stitches cutting out do not occur.

Adult↗
PubMed1988

Thyroid cartilage at the suprasternal notch with low situated thyroid gland.

The thyroid cartilage and thyroid gland forming a lump at the suprasternal notch is a surprising congenital anomaly which I believe has not been previously reported. A case with co-existent low hyoid bone, pharyngo-oesophageal junction and intrathoracic cricoid cartilage with no cervical trachea is presented. Its pathogenesis is suggested and its surgical importance is discussed.

Abnormalities, Multiple↗
PubMed1987

Low-frequency sensorineural hearing loss: a syndrome.

Eleven patients were found to have a pattern of bilateral, predominantly low-frequency sensorineural hearing loss and disproportionate speech discrimination scores. These patients were submitted to pure-tone audiometry, Arabic speech audiometry, immittance, auditory brainstem response, middle-latency response, Arabic central auditory tests, EEG and computerised tomographic (CT) scan. Results pointed to a lesion in the central auditory pathway. Two possible etiological factors were considered: infection and epilepsy of the temporal lobe. This disease pattern should raise the audiologist-otologist's index of suspicion necessary for its identification and planning of further investigations. This will help determine the etiology and true nature of the syndrome.

Adolescent↗