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Biomedical subjects

S M Stepanenko

Publications and source records attributed to S M Stepanenko.

23 records · Page 2Linked to original sources
PubMedDate not supplied

[Changes in the homeostatic indices in children with the prolonged crush syndrome receiving complex intensive therapy].

Crush syndrome was assessed clinically in 22 children, 16 of whom had renal failure. For objective evaluation, different techniques of extracorporeal detoxication were performed under dynamic control over the level of some homeostasis parameters. It has been established that the most marked changes were associated with the signs of colloid-osmotic condition and the following development of hyperosmolar syndrome. A complex approach to the management of this group of patients, using various intensive care techniques (plasmapheresis, hemodialysis, hemosorption, hyperbaric oxygenation, etc.) is assessed. Using the data of biochemical control, the most informative parameters characterizing the severity of crush syndrome in children have been determined.

Adolescent↗
PubMedDate not supplied

[Disorders of hemodynamics and their correction in children with nonhepatic portal hypertension during the course of surgical treatment].

Twenty children with the extrahepatic portal hypertension syndrome were examined; echo- and doppler-cardiography were employed to assess the central hemodynamic status before and after mesenterial-caval H-shunting, making use of a vascular insert from the internal jugular vein. The status of the circulatory system varied in the patients prior to surgery, and a risk group was distinguished with the maximal deviations of the hemodynamic parameters from the age-specific norms. 70% of the patients developed within 3 h after surgery pulmonary hypertension and right-ventricular dysfunction in the presence of a drastic rise of venous reflux to the right heart. Later an attempt was made at correction of the circulatory disorders by dopamine infusion at the rate of 3-6 micrograms/(kg.min) (19 patients). The authors emphasize that directly after shunting inotropic dopamine maintenance is necessary to prevent the development of hemodynamic disorders.

Adolescent↗
PubMedDate not supplied

[Energy metabolism during intensive care of children in the early postoperative period].

Energy metabolism have been investigated using indirect calorimetry technique combined with determination of daily nitrogen excretion with urine, in the early postoperative period in children, aged 4 to 14 years after thoracic surgery. No significant increase in total energy expenditure in the earliest postoperative period have been observed. The changes were associated predominantly with the structure of energy expenditure and were most vividly manifested in younger children aged 4 to 8 years.

Adolescent↗