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Biomedical subjects

S Macqueen

Publications and source records attributed to S Macqueen.

4 recordsLinked to original sources

Rhizopus microsporus in wooden tongue depressors: a major threat or minor inconvenience?

The investigation and management of an apparent outbreak of Rhizopus spp. in a London paediatric referral centre between September 1995 and April 1996 is described. The organism was identified in microbiological surveillance samples from 23 patients nursed in four hospital areas. Investigations revealed the presence of the organism in spatulae from all ward areas investigated and from closed boxed containers held in the central hospital stores obtained from a new supplier. In contrast, culture of spatulae from the initial supplier failed to yield any fungal isolates. The incident was reported to the Medical Device Agency (MDA), the Central Public Health Laboratory Service (CPHLS) and the Birmingham PHLS. A statement was prepared for the weekly Communicable Disease Report and a hazard warning issued by the MDA. The spatulae were withdrawn from use and the contract with the original supplier was re-established. This incident resulted in contamination of samples only and no patient involvement. It highlights the problems which may follow use of equipment for unintended purposes and the need for good manufacturing practice guidelines to be applied to non-sterile equipment used in direct patient care.

Child

Anthropology and germ theory.

A small study of biomedical cultural influences which affect the implementation of infection control practice was undertaken. The study, between March and September 1992, was performed in a 10-bedded paediatric cardiac intensive care unit and a total parenteral nutrition (TPN) outpatient clinic in a paediatric hospital in London. An ethnographic approach incorporating participant observation of six ritualistic practices and semi-structured interviews from seven people experiencing hospital-acquired infection was undertaken. A phenomenological, analytical method was used in an attempt to give meaning to the experience and behaviour of nurses, doctors and parents. The study indicated that 'germ theory' did not equate to nursing or medical practice but that the culture of biomedicine may interfere with infection control knowledge which causes conflict of understanding.

Anthropology, Cultural

Immunity to varicella-zoster virus in a normal adult population.

Sera from 489 trainee nurses were examined, by the ELISA technique, for the presence of varicella-zoster virus specific antibody; antibody was found in 446 (91.2%). In more detailed investigations of specific immunity in 33 healthy adults with a past history of chickenpox, 32 (97%) showed a positive lymphocyte transformation test, but only 11 out of 23 examined (48%) demonstrated mononuclear cell production of specific antibody in vitro; serum antibody was found in 30 (91%) by the ELISA and in 25 out of 26 examined (96%) by the FAMA technique. A high degree of correlation was found between both a positive lymphocyte transformation and the presence of serum antibody and a past history of chickenpox.

Adult

Positive practice.

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Acquired Immunodeficiency Syndrome