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Biomedical subjects

S Maj

Publications and source records attributed to S Maj.

At least 73 records · Page 4Linked to original sources
PubMedDate not supplied

The incidence of metamizole sodium-induced agranulocytosis in Poland.

Metamizole sodium continues to be used extensively as an analgesic in Poland. This study was the first undertaken to quantify the incidence of agranulocytosis associated with metamizole sodium in Poland, and to compare the findings with those from other countries. Based on data obtained retrospectively from medical records covering the period 1997-2001 in six haematology centres representative of Poland as a whole, the crude estimate obtained was a rate of 0.2 cases per million person-days of use. This is the same order of magnitude as the value from an epidemiological study covering several countries (0.3-4.0).

Administration, Oral↗
PubMedDate not supplied

[Effect of hydroxyurea treatment on free nucleotides in leukemic leukocytes].

An increase was observed in the pool of free nucleotides of leukaemic leucocytes during treatment with hydroxyurea, which was used as a drug inducing remission in chronic myeloid leukaemia and as an agent synchronizing the cell cycle in the so-called synchronization treatment of acute myeloid leukaemia. The increase in the amount of free nucleotides may depend on their increased synthesis and on their less extensive utilization for synthesis of nucleic acids. According to the authors the observed changes in the pool of free nucloetides may possess certain therapeutic implications.

Adolescent↗