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S Malobabić

Publications and source records attributed to S Malobabić.

At least 19 recordsLinked to original sources

[Anterior cruciate ligament (ACL)].

The anterior cruciate ligament or ACL (ligamenturn cruciatum anterius) is often injured, either alone or within complex ligament injuries of the knee. Therefore, the knowledge of detailed anatomic (macro- and micro-morphological) characteristics of this ligament is of key importance in therapy. The anatomy, structure, insertions, vascularization and inervation of the anterior cruciate ligament of the knee are described from the aspect of modern treatment and rehabilitation methods.

Anterior Cruciate Ligament↗

Third coronary artery in monkey heart.

Investigations were carried out on 55 monkey (Cercopithecus aethiops, Macaca fascicularis) hearts by stereomicroscopic dissection and measurements. Latex-injected specimens and corrosion casts showed that, as in humans, the hearts were usually (in 98.2% of the cases) supplied by two coronary arteries (CAs)--the left (LCA) and the right coronary artery (RCA), and occasionally (in 1.8% of the cases) also by a third one (TCA). Furthermore, the orifice of the TCA was situated in the right aortic sinus at the same level as the RCA and 0.2 mm in front of it. The LCA and the RCA originated from the corresponding aortic sinuses and the external diameter of the LCA was greater [average: 1.65+/-0.39 (SD) mm] than that of the RCA [average 0.94+/-0.15 (SD) mm] and the TCA (0.8 mm). The LCA orifice was more often above (76.3%) than below the free edge of the left aortic valve leaflet. The longitudinal axis of the aortic root and of the initial part of the LCA formed an angle of 45-120 degrees (average: 52 degrees). The orifice of the RCA was usually above (82.3%) the free edge of the right aortic valve leaflet, and less frequently below it (17.7%). The longitudinal axis of the aortic root and of the initial part of the RCA formed an angle of 70-150 degrees (average: 103 degrees). The resemblance of monkey CAs to their human counterparts make them a suitable model for experimental studies on coronary circulation.

Animals↗

Different neuronal and glial cell groups in corticomedial amygdala react differently to neonatally administered estrogen.

The percentage of labeled neurons and glial cells in the phylogenetically older corticomedial part of the amygdala was investigated in control and estrogen-treated rats using [3H]thymidine autoradiography. Newborn, three-day-old female and male Wistar rats were treated with a single dose of 1 mg of estrogen and killed at the age of 10 days. The percentage of labeled neuronal and glial cells was determined by stereological methods in the medial, cortical and central nuclei, respectively. In treated male rats, the percentage of labeled neurons and glial cells in these nuclei was significantly greater on the 10th day of life as compared to controls, except for glial cells in the nucleus centralis. In treated female rats, the percentage of labeled neurons in all three nuclei was comparable to controls, while the percentage of labeled glial cells was increased in the nucleus medialis, decreased in the nucleus centralis and unchanged in the nucleus corticalis. Our results indicate clear sex- and region-specific differences in the reactivity of both neurons and glia to neonatally administered estrogen.

Amygdala↗

[Morphologic asymmetry of the frontal lobe of the cerebral hemisphere in man].

The morphology and the left-right asymmetry of the frontal lobe convexity (sulcus frontalis superior and inferior, sulcus precentralis, gyrus precentralis, gyrus frontalis superior and medius) were studied on 19 formaline fixed human brains. During the study, the gyral and sulcal patterns were marked as similar, partially similar or different. Sulcal patterns on the left and right side were completely different (in at least more than half) in the greatest number of cases. Gyral patterns were also asymmetric (mirror image analysis). However, using the "essential gyral line"--the line indicating longitudinal gyral axis--the results changed dramatically. The majority of patterns appeared to be very similar, indicating that the method of analysis largely influences the results of morphological studies of human brain asymmetry. This explains different findings reported in the literature. We suggest that the use of the "essential gyral line" provides standardized method of morphological analysis, which was not available up to date.

Adult↗

Golgi morphology of the neurons in frontal sections of human interthalamic adhesion.

The Golgi morphology of the neurons in the human interthalamic adhesion (IA, which is not present in every human brain) is very variable. Four types of Golgi-impregnated neurons were found in the adult human IA: (1) fusiform neurons (most characteristic of the human IA); (2) neurons with an oval perikaryon; (3) triangular neurons (rarely found), and (4) multipolar neurons (polygonal perikaryon and at least 4 primary dendrites). Fusiform neurons, as well as triangular and multipolar ones, belong to the isodendritic type, but the neurons with oval perikarya do not.

Adult↗

Anatomy of the pericallosal pial plexus in man.

Fine arterial branches on the superior surface of corpus callosum were investigated on 22 human brains under stereomicroscope. These branches were directed toward: 1. the upper surface of corpus callosum (3-6 branches, mean 8), 2. the depths of the sulcus corporis callosi (4-13 branches, mean 7), and 3. the cingulate gyrus (1-10 branches, mean 5). All the vessels composing the pericallosal pial plexus have a uniformed caliber of 0.9-0.6 mm at their origins, and 0.7-0.3 mm after branching. In 9 cases a longitudinal vessel within the stria longitudinalis medialis, connected with the pial plexus was found. Important details of morphology of this plexus and their significance are discussed.

Arteries↗

Alexia with agraphia.

The authors presented a case of relatively pure syndrome of alexia with agraphia in a patient speaking Serbo-Croatian language. Reading disturbances showed some characteristics of a deep dyslexia. Besides severely impaired reading and writing abilities, some components of Gerstamnn's syndrome were also present. Infarction in the posterior half of the left supramarginal and in the anterior half of the left angular gyrus was accurately located by the graphic reconstruction of CT scans.

Agraphia↗

Anatomic basis for surgical approach to the distal segment of the posterior cerebral artery.

The distal segment of the posterior cerebral artery (PCA), which extends from the junction with the posterior communicating artery to its terminal division into the parieto-occipital and calcarine arteries, was examined in 37 brains. Three types of distal segment were distinguished. In the first type (42.9%), the terminal division was located either in the calcarine sulcus or in the quadrigeminal cistern. In the second type (41.4%), the terminal division had the same position, but the distal segment, in addition to its terminal stems, also gave off the common temporal artery. In the third type (15.7%), the terminal division was seen in the ambient cistern. The distal segment of the PCA gave rise to several collateral branches: the collicular artery (2.8%), the anterior (28.6%), middle (30.0%), and posterior (28.6%) hippocampal arteries, the proximal (82.9%) and distal (20.0%) lateral posterior choroidal arteries, the proximal (40.0%) and distal (41.4%) medial posterior choroidal arteries, the peduncular, thalamogeniculate and splenial branches, the lingual gyri artery and the temporal arteries. Several anatomic variants of the distal segment were observed in this study: fenestration of the distal segment (1.4%), location of the distal segment dorsal to the uncus (2.8%), origin of the collicular (2.8%) and anterior choroidal arteries (1.4%) from the distal segment, and protrusion of the parieto-occipital arterial loop into the lateral ventricle (2.8%). The authors discuss the clinical significance of these anatomic data.

Adult↗

Morphology of the human corpus callosum: the shape of its mediosagittal section.

The shape of the corpus callosum was studied on mediosagittal sections of 50 human brains. The terms "facies corticalis" and "facies profunda" are proposed for the sides of corpus callosum. Each of 50 brains had a different shape of callosal mediosagittal section and any available classification was not possible. In 94% of cases, the contour of callosal cortical surface exhibited a posterior depression and in 46% also an anterior one. Other details of callosal morphology influencing its shape on mediosagittal section (transverse folds, circumscribed depressions) were described. The junction of fornix and corpus callosum in 78% was in 3rd and in 14% in 4th quarter of callosal length. The possible significance of these findings for further studies of human brain morphology is discussed.

Adult↗

Size and position of the human adhaesio interthalamica.

In 50 human brains, we investigated the size of the adhaesio interthalamica, length of CA-CP line, position of the centre of adhaesio interthalamica, and the distance between the corpus callosum and adhaesio interthalamica. Interthalamic adhesion was absent in 11 brains (22%) and was duplicated in 1 brain. In all 50 brains, length of the intercommissural line (CA-CP) had a mean value of 2.56 cm, in brains with the interthalamic adhesion 2.48 cm, and 2.56 cm in brains without it. t-test for this difference showed no significant result for a probability of 0.05 (t = 1.95). Midsagittal section area of adhaesio interthalamica had a mean value of 13.1 mm2 (min = 1.5 mm2; max = 34 mm2). There is no correlation between the length of CA-CP line and the size of the midsagittal section area of adhaesio interthalamica (the correlation coefficient was 0.06). The centre of adhaesio interthalamica was most often situated above the CA-CP line and around the perpendicular line through its middle portion. The distance between the corpus callosum and interthalamic adhesion, measured in standardized system of CA-CP line, had a mean value 1.4 cm (min = 0.7 cm; max = 2.3 cm). Our results confirm the opinions that the presence of size of the interthalamic adhaesion depends not directly on the size of the corresponding brain (diencephalon).

Adult↗

Significance of the encephalometric parameters of human corpus callosum and medial hemispheric surface.

11 encephalometric parameters of the corpus callosum and medial hemispheric surface have been measured on 50 human brains fixed in 7% formaline solution. The measurement of linear parameters has been made by using a standardized encephalometric system of reference, based on the bicommissural line which has been widely used in neurosurgery. The applied statistical procedures have shown that the following variables are the most successful in the evaluation and prediction of the change of the midsagittal cross-sectional corpus callosum area in the following order: the thinnest part of the corpus callosum, the corpus callosum length and medial hemispheric border. Their change for the unit value causes an average change of the corpus callosum midsagittal section surface area for the value of the partial regression coefficient with which they are connected. The chosen variables explain only the 45% variability of the cross-sectional corpus callosum surface area, and the remaining variability belongs to some other variables which have not been included in present investigation. The variability of the hemispheric length (74%), the corpus callosum length (65%) and medial hemispheric border length (64%) is most adequately explained on the basis of chosen variables.

Adult↗

On the neurons with dendrites intermingling with the fibers of the human corpus callosum: a Golgi picture.

Golgi preparations of the anterior part of the truncus of the corpus callosum from 11 adult human brains were investigated. The vertical plane of section was situated symmetrically between the frontal and sagittal plane. The use of this oblique plane of section enabled easy identification of the neurons with dendrites intermingling with transcallosal fibers, what was not possible in standard frontal sections. 2 types of such neurons (with features of other interstitial neurons) were described: fusiform and multipolar. Both types of neurons were more frequently impregnated in areas adjacent to induseum griseum, cingular cortex, and in the depth of the callosal sulcus. Multipolar neurons were also present in the central core and in ventral parts of the corpus callosum, but fusiform ones were not present in ventral parts of the corpus callosum truncus. The dentrites of both types of neurons usually were perpendicular to, sometimes also parallel to transcallosal fibers. The impregnation of these neurons in groups and pairs suggest their integrative role, and their planar orientation in mentioned oblique plane corresponds to oblique direction of transcallosal cingulostriatal decussating fibers.

Adult↗