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Biomedical subjects

S Manciulea

Publications and source records attributed to S Manciulea.

8 recordsLinked to original sources
PubMed1978

[The effect of various organochlorine pesticides on the immunologic reactivity of the white rat].

Wistar rats, aged 30 and 90 days, received Aldrin and Lindan treatment (8 ppm or 11 ppm) over 60 days, followed by inoculation of E. coli. The capacity of antibody formation was changed but not inhibited. Functional disorders occurred in the thymus (decline of nucleic acids), adrenal gland (decline of Vitamin C), and in the protein synthesis. The toxicity of even smaller Aldrin doses obviously was stronger than that of Lindan. The toxicity of either substance to younger animals was stronger than to individuals in more advanced age.

Adrenal Glands↗
PubMed1977

[Changes of some metabolic parameters of the liver in chickens under the influence of Entomoxan].

From the 3rd week of life Studler-Cornish-breed chickens received a food mixed with Entomoxan (15 ppm HCH-gamma-Isomer in the food) for an 8 weeks period. 2,4,6, and 8 weeks after the beginning of the experiment livers of the chickens were examined for RNA-, DNA-, total protein- and total aminonitrogen contents. The RNA-values decrease constantly where as those of DNA increase up to the 4th week and after that decline. Total protein contents rise up to the 4th week. After 2 and 8 weeks the contents of amino-nitrogen are lower in experimental birds than in controls.

Animals↗
PubMed1976

[Changes in various physiological parameters in chickens after entomoxan administration].

Eight weeks of Entomoxan administration to chickens (15 mg/kg live weight) were followed by significant change of certain physiological parameters relating to the blood, liver, suprarenal bodies, and sexual glands. Such variation was taken to indicate the presence of stress suffered by the animals' impairment of carbohydrate and fat metabolism, and defects of hormonal regulation.

Adrenal Glands↗
PubMed1975

[Thymus changes in chicks following treatment with small doses of insecticides].

Effects of small doses of insecticides (Fenclorfos and Heptaclor) upon the thymus of chickens were followed. Treatment began at the age of 3 weeks and continued during 4 or 8 weeks. Doses used were: 1 ppm for Heptaclor and 1 ppm and 0.5 ppm for Fenclorfos. Total nucleic acid, total protein, RNA, DNA, and amino acid nitrogen contents were determined, as well as GOT and GPT activities and weight of the organ. Results are interpreted as being due to the action of insecticides on the hypothalamus-hypophysis-adrenals axis. They depend on the nature and dosis of insecticide, as well as on the duration of the treatment.

Adrenal Glands↗