PubMed Health⌕ Search

Biomedical subjects

S Markowitz

Publications and source records attributed to S Markowitz.

82 records · Page 5Linked to original sources
PubMedDate not supplied

Cytologic detection of cervical granuloma inguinale.

Two cases of granuloma inguinale detected cytologically on routine Papanicolaou-stained cervical smears are presented; the cytologic and histologic features are described in detail, and the electron microscopic appearances are shown. The suitability of the Papanicolaou stain in the detection of granuloma inguinale is discussed, with emphasis on possible differential diagnoses to be considered. It is concluded that a definitive diagnosis of granuloma inguinale can be made on routine Papanicolaou-stained smears showing the following spectrum of changes: intact capillaries indicative of epithelial and stromal ulceration; a marked inflammatory cell infiltrate consisting predominantly of neutrophils; epithelioid histiocytes representing granuloma formation; and Donovan bodies located in characteristic single or multiple intracytoplasmic vacuoles within large histiocytes. Recognition of this cytologic picture may enable early diagnosis, even in nonendemic areas, of a potentially disfiguring venereal disease.

Adult↗
PubMedDate not supplied

Innovation in international training in occupational and environmental health: challenging unspoken assumptions.

The Department of Community and Preventive Medicine of the Mount Sinai School of Medicine, in collaboration with Queens College of the City University of New York, is conducting a research training program in cooperation with partner institutions in Mexico, Brazil, and Chile to assist them to develop an enhanced capacity to identify, document, and ameliorate environmental and occupational health problems of major public significance. The Fogarty International Center of the National Institutes of Health sponsors the program, which focuses on tailoring training to the host countries' needs and conditions. The program's centerpiece is the Selikoff Fellowship, which had been awarded to 15 Fellows by 1998. Each Fellow spends three one-month training periods in New York, interspersed with distance learning, and, with the help of a mentor, completes a research project in the home country. Details of the program are provided.

Brazil↗
PubMedDate not supplied

Primary prevention of occupational lung disease: a view from the United States.

Occupational lung diseases are an important source of preventable morbidity and mortality in the United States. A significant proportion of lung cancer, mesothelioma, asbestosis and the other pneumoconioses, asthma, and chronic obstructive pulmonary disease, is caused by well-established occupational agents, especially among selected subgroups of the general population. Primary prevention of this set of diseases requires identification and control of workplace hazards. In the United States, data from inspections undertaken by the Occupational Safety and Health Agency, and from periodic surveys conducted by the National Institute for Occupational Safety and Health, show that respiratory toxins are commonly found in the workplace. Workplace-based education, surveillance and exposure reduction and elimination are essential components of a strategy to prevent occupational lung disorders.

Health Surveys↗
PubMedDate not supplied

Endometriosis of the rectovaginal septum. Diagnosis by fine needle aspiration cytology.

The cytologic picture seen in two cases of rectovaginal endometriosis diagnosed by fine needle aspiration (FNA) cytology is presented in detail. The cell pattern differed considerably from that previously described in fluid specimens and more closely resembled the exfoliation observed in direct endometrial samples. No previous report appears to exist on the diagnosis of rectovaginal endometriosis by FNA.

Adult↗
PubMedDate not supplied

Vascular head pain: a neurobiologist's approach.

Cephalic blood vessels are invested with a dense network of perivascular fibers of diverse origin. A proportion of these fibers arise from trigeminal neurons and contain chemicals which have vasodilating and pro-inflammatory properties. Evidence suggests that these trigeminovascular neurons may influence both vascular function and neurophysiological activity within the brain. The trigeminovascular system may thus represent a (bi-directional, brain-vessel, vessel-brain) final common pathway for the actions of many chemical, mechanical and neural influences which may have important consequences for the pathogenesis and treatment of headache.

Animals↗
PubMedDate not supplied

Cytologically detected chlamydial changes and progression of cervical intraepithelial neoplasias. A retrospective case-control study.

Fifty-four patients with Chlamydia-associated changes on the cervical smears, in whom adequate follow-up had been obtained over a two-year period, were investigated. The progression to biopsy-proven cervical intraepithelial neoplasia (CIN) III in this group was 42.6%, significantly higher than the 15.8% progression rate noted in a control group of patients with similar cytologic abnormalities but unassociated with Chlamydia. This finding suggests that Chlamydia may be a cocarcinogen or a potentiating agent in the progression of CIN.

Adult↗