[Congenital developmental anomalies in the offspring of epileptic mothers].
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Abnormalities, Drug-Induced↗
Biomedical subjects
S Marosfi
Publications and source records attributed to S Marosfi.
Human tolerability studies with D-Met2,Pro5-enkephalinamide.
As reported previously D-Met2,Pro5-enkephalinamide (EA) is a highly active enkephalin analogue. To examine its human tolerability male volunteers were treated s.c. with increasing doses (0.1-30.0 mg). The observed autonomic effects were as follows: feeling of heaviness in the limbs, dry mouth, pallor of the face and conjunctival injection. There was no significant change in blood pressure, pulse and respiratory frequency. The autonomic effects appeared within 15-30 min. However, its effects on mood and wakefulness i.e. slight drowsiness, decrease in psychic tension and emotional detachment developed only later. The serum prolactin level increased dose-dependently, while the growth hormone (HGH) content showed biphasic dose-response pattern. The TSH content increased only at the highest doses applied (10.0-30.0 mg).
Adult↗
A study of periodicity and structure of EEG complexes in a case of SSPE.
This is a preliminary study of the EEG complexes of SSPE. This consisted of an analysis of the time and frequency domain of the complexes recorded in different test situations. The authors examined the periodicity of complexes and changes in the intercomplex interval succession and, in another approach, the shape of the complex and the constant properties of its structure. Analysing the findings obtained and the data of earlier authors, they suggested a working hypothesis according to which a regulated trigger mechanism 'sparks off' the structures 'sensitive' to this in different regions of the cortex, in which simultaneous and successive sub-processes lasting several hundred milliseconds then occur; the periodic complex appearing in SSPE is that part of this that can be observed in the EEG.
Adult↗
Beyond principal component analysis: canonical component analysis for data reduction in classification of EPs.
The authors tested a new procedure for the discrimination of EPs obtained in different stimulus situations. In contrast with principal component analysis (PCA) used so far for the purpose of data compression, the method referred to as canonical component analysis (CCA) is optimal for the purpose of discrimination. To illustrate this, the authors performed both PCA and CCA for the same material, then after carrying out discriminant analysis ( SWDA ) for the data transformed in this way, compared the performance of the two procedures in discrimination. In view of both the theoretical and practical considerations, the authors recommend that in the future researchers use CCA instead of PCA in EP studies for data reduction carried out for discrimination.
Computers↗