Biomedical subjects

S Martínez-Calvo

Publications and source records attributed to S Martínez-Calvo.

4 recordsLinked to original sources

PubMed2006

[Visual symptoms as the first manifestation of Alzheimer's disease].

CASE REPORT: We report a 59-year-old patient with difficulty in visual perception, difficulty reading and episodes of dyschromatopsia. The ocular examination was unremarkable. Structural neuro-imaging and neuro-ophthalmology tests were normal. Positron emission tomography scanning showed decreased metabolism in the parieto-occipital cortex bilaterally. Several months later the patient developed Alzheimer's disease. DISCUSSION: Visual symptoms may be the first manifestation of Alzheimer's disease.

Alzheimer Disease↗

PubMed2006

[Severe ocular side effects with Topamax].

CASE REPORTS: We describe 2 patients who developed ocular side effects during treatment with topiramate. One was a 16-year-old woman with generalized seizures who developed a homonymous hemianopia after using topiramate 125 mg per day for 12 weeks, and the other was a 24-year-old epileptic female who developed a bilateral maculopathy after using topiramate 150 mg per day for 8 weeks. DISCUSSION: We identified two severe ocular adverse reactions from topiramate. Both reactions necessitated discontinuing the treatment, but the topiramate-associated maculopathy was irreversible.

Adolescent↗

PubMed2006

[Tuberculous papillitis].

CASE REPORT: We describe a 65-year-old asymptomatic woman with unilateral optic disc edema. Laboratory testing revealed a very marked positive PPD (25 mm) with dermatolysis. Anti-tuberculosis therapy resulted in complete resolution. DISCUSSION: Tuberculosis should be considered in the diagnosis of papillitis, even in asymptomatic patients.

Aged↗

PubMed2005

[Acute zonal outer occult retinopathy].

CASE REPORT: In May 2001 a 10-year-old boy, examined 3 months after the development of a large temporal scotoma in the right eye, was diagnosed with photopsia. The fundus appeared normal, visual field examination revealed a large temporal defect and, in July 2001, electroretinography (ERG) was nonrecordable. The left eye was normal. The field defects and ERG abnormality remained 4 years later, and the fundus developed a sharply demarcated zone of atrophy of the RPE. DISCUSSION: We report a typical case of acute zonal occult outer retinopathy (AZOOR). Although rare, its symptoms are variable, and its shape is not characteristic, making it difficult to make the correct diagnosis.

Acute Disease↗