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Biomedical subjects

S Masmoudi

Publications and source records attributed to S Masmoudi.

26 records · Page 2Linked to original sources

[Persistent sciatic artery. Apropos of a new case].

We report a new case of persistent sciatic artery. An 18-year-old girl was hospitalized with ischemia of the left foot. An arteriogram demonstrated a sciatic artery completely persistent. The superficial femoral artery was hypoplasic. A left femoro-popliteal by pass with saphenous vein graft was practised. After the operation, the patient did well and had no complications. We present this observation with a literature review about clinical arteriographic and surgical aspects of this vascular structure and its complications.

Adolescent↗

[A new case of false aneurysm of the superior mesenteric artery].

We report a case of successful management of a false aneurysm of the superior mesenteric artery. The only helpful clinical manifestations were episodes of previous abdominal pain and a history of bacterial endocarditis. The surgical management involved endo-aneurysmorrhaphy. The patient's post-operative course was unremarkable.

Adult↗

[Arteritis of the lower limbs in diabetics].

37 cases of diabetic arteritis of lower limbs in diabetic patients were retrospectively studied, from 1988 to 1991. Mean age was 66 years. Masculine predominance was evident with a sex ratio of 1/10. The majority of our patients have consulted at a late stage with trophic disturbance of inferior limbs, indeed 18 patients were seen at the 4th stage. Mortification was observed in 55% cases. Arteriography has allowed to show an elective localization of lesions at the femoralis arteria, profunda femoralis arteria and distal axes. Operative indication was made in 22 patients. Conservative surgery was performed for 50% of the operated patients. Conservative surgery results had been relatively less satisfactory than for others arteritis, particular because of late consultation and the condition of diabetic patients.

Aged↗

[Takayasu disease. Diagnostic criteria and therapeutic procedure].

A study of 11 cases of Takayasu's disease, collected from the cardio-vascular surgical service of Sfax, has been realized during the 4 year-period from 1988 to 1991. Womanly predominance was neat. The average age was 40 years, with extremes of 24 and 56 years. Dominant revealing symptoms was upper limb ischaemia found in 9 cases, a reno-vascular hypertension rebelled to medical treatment was noted in 2 cases. Arteriography have showed a preferential localization of lesions in the subclavian artery essentially at the post-vertebral segment. Lesions types were dominated by stenosis and obliteration, then aneurysms were rare. Operative indication was posed in 9 cases. 11 revascularisations procedures were performed of which 10 arterial by passes and one resection graft. Two bypasses were obstructed, the 9 remaining bypasses have a good previous checked clinically and by angiography (or echo-doppler) with a mean follow-up of 14 months.

Adult↗

Contribution of DFNB1 and DFNB2 loci to neurosensory deafness in affected Tunisian families.

Classical studies have demonstrated genetic heterogeneity for nonsyndromic autosomal recessive congenital neurosensory deafness. The first two DFNB1 and DFNB2 locations were found using two consanguineous Tunisian families respectively from north and south. We tested these loci for cosegregation with deafness in twenty four southern families with nonsyndromic presumed congenital sensorineural deafness and a pedigree structure consistent with autosomal recessive inheritance. Only in our families, did deafness cosegregate with DFNB1. Although our families are from the south, none of them showed linkage to DFNB2.

Chromosome Segregation↗

[Prevalence of celiac disease serological markers in Tunisian type 1 diabetic adults].

OBJECTIVE: to evaluate the prevalence of celiac serological markers; anti-transglutaminase (ATGt), anti-endomysium (AE), anti-gliadin (AGD) and anti-reticulin (AR) antibodies; in type 1 diabetic Tunisian adults. SUBJECTS AND METHODS: 261 type 1 diabetic patients aged from 16 to 60 years were enrolled in this prospective study. IgG and IgA transglutaminase and gliadin were measured with ELISA. IgA AE were tested by indirect immunofluorescence using 2 substrates; monkey oesophagus and human umbilical cord. AR were detected by indirect immunofluorescence on rat liver, kidney and stomach. Sera IgA level was measured by turbidimetry. RESULTS: 83/261 of diabetics were positive for at least one antibody, 5.7% had ATGt-A, 3.4% AE on monkey esophagus, 3.1% AE on umbilical cordon, 18% AGD-A, 19.5% AGD-G and 3.1% AR. There was an excellent concordance between AE and ATGt (r = 0.9). Out of the 261 diabetics, 5 had an IgA deficiency and one of them has IgG AE and ATGt. CONCLUSION: serological markers of celiac disease seem to be frequent in diabetics. Nevertheless, diagnosis must be confirmed by histological studies which allow us to know the real prevalence of celiac disease in diabetic adults.

Adolescent↗